Squamous cell carcinoma arising from chronic osteomyelitis is uncommon. Although the majority of cases occur in the lower extremity, incidence in the foot is relatively rare, and in the toe, exceptional. This report illustrates a particularly unusual incidence of squamous cell carcinoma complicating chronic osteomyelitis of the hallux. Guidelines for early diagnosis, recommendations for treatment, and prognostic data are included.
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References
1.
. BenedictE.B.: Carcinoma in osteomyelitis. Surg. Gynecol. Obstet., 53:1–11, 1979.
2.
. BerestonE.E.NeyC.: Squamous cell carcinoma arising in a chronic osteomyelitic sinus tract with metastasis. Arch. Surg., 43:257–268, 1941.
3.
. CappelloJ.C.DonickI.I.: Squamous cell carcinoma as a complication of chronic osteomyelitis. J. Foot Surg., 20:136–141, 1981.
4.
. FitzgeraldR.H.BrewerN.S.DahlinD.C.: Squamouscell carcinoma complicating chronic osteomyelitis. J. Bone Joint Surg., 58A:1146–1148, 1976.
5.
. GiuntiA.LausM.: Malignant tumours in chronic osteomyelitis. (A report of thirty nine cases, twenty six with long term follow up.) Ital. J. Orthop. Traumatol., 4:171–182, 1978.
6.
. HejnaW.F.: Squamous-cell carcinoma developing in the chronic draining sinuses of osteomyelitis. Cancer, 18:128–132, 1965.
7.
. HendersonM.S.SwartH.A.: Chronic osteomyelitis associated with malignancy. J. Bone Joint Surg., 18:56–60, 1936.
8.
. HobartM.H.MillerD.S.: Unusual complications of osteomyelitis. Am. J. Surg., 45:53–59, 1939.
9.
. JohnsonL.L.KempsonR.L.: Epidermoid carcinoma in chronic osteomyelitis: diagnostic problems and management. J. Bone Joint Surg., 47A:133–145, 1965.
. LifesoR.M.BullC.A.: Squamous cell carcinoma of the extremities. Cancer, 55:2862–2867, 1985.
12.
. LovellW.W.KingR.E.AlldredgeR.: Carcinoma in skin, sinuses and bone following chronic osteomyelitis. South Med. J., 50:266–271, 1957.
13.
. McNallyA.K.DockertyM.B.: Carcinoma developing in chronic draining cutaneous sinuses and fistulas. Surg. Gynecol. Obstet., 88:87–96, 1949.
14.
. PatelA.RyanJ.F.BadrinathK.ChenS.C.: Squamous cell carcinoma of the toe masquerading as osteomyelitis. J. R. Soc. Med., 81:418–420, 1981.
15.
. Sankaran-KuttyM.CoreaJ.R.AliM.S.KuttyM.K.: Squamous cell carcinoma in chronic osteomyelitis. Report of a case and review of the literature. Clin. Orthop., 198:264–267, 1985.
16.
. SedlinE.D.FlemingJ.L.: Epidermoid carcinoma arising in chronic osteomyelitic foci. J. Bone Joint Surg., 45A:827–838, 1963.
17.
. TaylorG.W.NathansonI.T.ShawD.T.: Epidermoid carcinoma of the extremities with reference to lymph node involvement. Ann. Surg., 113:268–275, 1941.
18.
. VishniavskyS.: Squamous cell carcinoma in sinus tract of chronic osteomyelitis. Va. Med. Mon., 97:645–650, 1970.
