A patient with carcinoma cuniculatum of the foot, an uncommon tumor, is presented. This tumor, also reported as verrucous carcinoma and epithilioma cuniculatum, is a low-grade, squamous cell carcinoma of the skin that rarely metastasizes. The highly keratinizing lesion has a locally destructive course, but with treatment by excision, it has a low recurrence rate.
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References
1.
AckermanL.V.Verrucous carcinoma of the oral cavity. Surgery, 23: 670–678, 1948.
2.
AirdI.JohnsonH.D.LennoxB.Epithelioma cuniculatum: variety of squamous cell carcinoma to the foot. Br. J. Surg, 42: 245–250, 1954.
3.
BrownsteinM.H.ShapiroL.Verrucous carcinoma of the skin. Cancer, 38: 1710–1716, 1976.
4.
DemianS.D.E.BushkinF.L.EschevarriaR.A.Perineural invasion and anaplastic transformation of verrucous carcinoma. Cancer, 32: 395–401, 1973.
5.
KaoG.F.GrahamJ.H.HelwigE.B.Carcinoma cuniculatum (verrucous carcinoma of the skin). Cancer, 49: 2395–2403, 1982.
6.
MoraR.G.Microsurgically controlled surgery (Mohs' chemosurgery) for treatment of verrucous squamous cell carcinoma of the foot (epithelioma cuniculatum). J. Am. Acad. Dermatol. 8: 354–362, 1983.
7.
PerezC.A.KransF.T.EvansJ.C.Anaplastic transformation in verrucous carcinoma of the oral cavity after radiation therapy. Radiology, 86: 108–115, 1966.
8.
ProffittS.D.SpoonerT.R.KosekJ.C.Origin of undifferentiated neoplasm from verrucous carcinoma of the oral cavity following irradiation. Cancer, 26: 389–393, 1970.
9.
ReingoldI.M.SmithB.R.GrahamJ.H.Epithelioma cuniculatum pedis, a variant of squamous cell carcinoma. Am. J. Clin. Pathol., 69: 561–565, 1978.
