What Are the Predictors of Treatment Failure in Patients Who Have Undergone Two-Stage Exchange for Infected Total Ankle Arthroplasty (TAA)?

Abstract

Recommendation:

Predictors for treatment failure in patients undergoing 2-stage exchange for infected total ankle arthroplasty (TAA) include compromised soft tissues (eg, sinus tract and exposed hardware), significant bone involvement/osteomyelitis, and insufficient timing of antibiotic course before reimplantation.

Level of Evidence:

Moderate.

Delegate Vote:

Agree: 100%, Disagree: 0%, Abstain: 0% (Unanimous, Strongest Consensus).

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References

Buechel

Femino

D’Alessio

. Primary exchange revision arthroplasty for infected total knee replacement: a long-term study. Am J Orthop. 2004;33:190-198; discussion 198.

Del Pozo

Patel

. Clinical practice. Infection associated with prosthetic joints. N Engl J Med. 2009;361:787-794.

Frank

Kayupov

Moric

et al . The Mark Coventry, MD, Award: Oral antibiotics reduce reinfection after two-stage exchange: a multicenter, randomized controlled trial. Clin Orthop Relat Res. 2017;475:56-61.

Gougoulias

Khanna

Maffulli

. How successful are current ankle replacements? A systematic review of the literature. Clin Orthop Relat Res. 2010;468:199-208.

Jackson

Schmalzried

. Limited role of direct exchange arthroplasty in the treatment of infected total hip replacements. Clin Orthop Relat Res. 2000;381:101-105.

Kessler

Knupp

Graber

et al . The treatment and outcome of peri-prosthetic infection of the ankle: a single cohort-centre experience of 34 cases. Bone Joint J. 2014;96-B:772-777.

Kessler

Sendi

Graber

et al . Risk factors for periprosthetic ankle joint infection: a case-control study. J Bone Joint Surg Am. 2012;94:1871-1876.

Lee

Cho

Hur

Yoon

. Perioperative complications of HINTEGRA total ankle replacement: our initial 50 cases. Foot Ankle Int. 2008;29(10):978-984.

Osmon

Berbari

Berendt

et al . Executive summary: diagnosis and management of prosthetic joint infection: clinical practice guidelines by the Infectious Diseases Society of America. Clin Infect Dis. 2013;56:1-10.

10.

Patton

Kiewiet

Brage

. Infected total ankle arthroplasty: risk factors and treatment options. Foot Ankle Int. 2015;36:626-634.

11.

Reuver

Dayerizadeh

Burger

Elmans

Hoelen

Tulp

. Total ankle replacement outcome in low volume centers: short-term followup. Foot Ankle Int. 2010;31:1064-1068.

12.

Scarborough

Rombach

et al . Oral versus intravenous antibiotics for the treatment of bone and joint infection (OVIVA): a multicentre randomised controlled trial. Orthop Proc. 2017;99-B:42.

13.

Winkler

Stoiber

Kaudela

Winter

Menschik

. One stage uncemented revision of infected total hip replacement using cancellous allograft bone impreg-nated with antibiotics. J Bone Joint Surg Br. 2008;90:1580-1584.

14.

Young

May

Haddad

. Infected total ankle arthroplasty following routine dental procedure. Foot Ankle Int. 2009;30(3):252-257.

15.

Zimmerli

Trampuz

Ochsner

. Prosthetic-joint infections. N Engl J Med. 2004;351:1645-1654.

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