Primary synovial chondromatosis is a rare benign condition characterized by the formation of multiple cartilaginous nodules in the synovium of joints and on occasions tendon sheaths or bursae. A case of primary synovial chondromatosis affecting the subtalar joint is reported. The patient's brother developed the same condition affecting the same joint 2 years later. The proposed etiologies are discussed including the presence of the proto-oncogene C-erb B-2.
ColesMJ-MTaraHT: Synovial chondromatosis: a case study and brief reviewAm. J. Orthop.26(1):37–40, 1997.
2.
DavisRIFosterHArthurKTrewinSHamiltonPWBiggartDJ: Cell proliferation studies in primary synovial chondromatosisJ. Pathol.184:18–23, 1998.
3.
DavisRIFosterHBiggartDJ: C-erb B-2 staining in primary synovial chondromatosis: a comparison with other cartilaginous tumoursJ. Pathol.179:392–395, 1996.
4.
DavisRIHamiltonABiggartDJ: Primary synovial chondromatosis: a clinicopathologic review and assessment of malignant potentialHuman Pathol.29(7):683–688, 1998.
5.
KennedyPTMcCoyGF: Synovial chondromatosis of a ⋆⋆⋆cubo-metatarsal jointUlster Med. J.65(1):95–97, 1996.
6.
LazarusESongJHLambiaseRETungGA: Cases of the dayRadioGraphics16:709–712, 1996.
7.
LeuJMantsubaraTHirohataK: Ultrastructural morphology of early cellular changes in the synovium of primary synovial chondromatosisClin. Orthop.276:299–306, 1992.
8.
ShpitzerTGanelAEngelbergS: Surgery for synovial chondromatosisActa Orthop. Scand.61(6):567–569, 1990.