Rupture of Achilles tendon (AT) is an uncommon complication of treatment with fluoroquinolones. We describe a case of bilateral tendinosis and rupture of the right AT in a patient who began levofloxacin treatment for community acquired pneumonia. Sonography showed thickening and hypoecogenicity of both AT and complete rupture and separation of the right Achilles tendon.
ChaslerieABannwarthBLandreauJMYverLBegaudB: Tendon rupture and fluro-quinolones: an undesirable effect of drug selection. Rev Rhum Mal Osteoartic, 59:297–298, 1992.
5.
De la Garza EstradaVACaballeroVazquez RCarranzaCamacho JL: Achilles tendon rupture and fluoroquinolones use: report of two cases. Arch Med Res, 28:429–430, 1997.
6.
GibbonWWCooperJRRadcliffeGS: Distribution of sonographically detected tendon abnormalities in patients with a clinical diagnosis of chronic Achilles tendinosis. J Clin Ultrasound, 28:61–66, 2000.
7.
KirschembaumSEKelmanC: Modification of the Lindholm procedure for plastic repair of ruptured Achilles tendon: a case report. J Foot Surg, 19:4–11, 1980.
8.
LewisJRGumsJGDickensheetsDLLevofloxacin-induced bilateral Achilles tendonitis. Ann Pharmacother1999; 33:792.
9.
LinJFesselDPJacobsonJAWeadockkWJHayesCW: An illustrated tutorial of musculoskeletal sonography. AJR, 175:637–645, 2000.
10.
LindholmA: A new method of operation in subcutaneous rupture of the Achilles tendon. Acta Chir Scand, 117:261, 1959.
11.
McGarveyWCSinghDTrevinoSGPartial Achilles tendon ruptures associated with fluoroquinolone antibiotics: a case report and literature review. Foot Ankle Int, 17:496–498, 1996.
12.
MeyboomRHBOlssonSKnolADekens-DonterJAMDe KoningGHP: Achilles tendinitis induced by perfloxacin and other fluoroquinolone derivatives. Pharmacoepidemiol Drug Saf, 3:185–189, 1994.
13.
RibardPAudisioFKahnMF: Seven Achilles tendinitis including three complicated by rupture during fluoroquinolone therapy. J Rheumatol, 19:1479, 1992.
14.
Van der LeidenPDvan de LeiJNabHWStrickerBHCh: Achilles tendinitis associated with fluoroquinolones. Br J Clin Pharmacol, 48:433–437, 1999.
