Tumoral calcinosis is characterized by periarticular deposition of calcium phosphate, usually in the setting of normocalcemia and hyperphosphatemia. The term tumoral calcinosis can be used to describe lesions with periarticular deposition of calcium phosphate resulting either from a primary disorder or a secondary disorder, such as renal failure with associated secondary hyperparathyroidism. Treatment entails phosphate deprivation, control of any primary disease processes such as secondary hyperparathyroidism, and resection for recalcitrant symptoms. We present a case of tumoral calcinosis involving the foot which required resection and ultimately hyperparathyroidectomy.
EnzingerFMWeissSW: Soft Tissue Tumors. St. Louis, Mosby Year Book, 1995. pp 1039–1045.
2.
FernandezEAmoedoMLBorrasMPaisBMontoliuJ: Tumoral Calcinosis in hemodialysis patients without severe hyperparathyroidism. Nephrol Dial Transplant8:1270–1273, 1993.
3.
KirkTSSimonMA: Tumoral Calcinosis: Report of a case with successful medical management. J Bone Joint Surg63A: 1167–1169, 1981.
McGregorDHMowryMCherianRMcAnawMPooleE: Nonfamilial tumoral calcinosis associated with chronic renal failure and secondary hyperparathyroidism: Report of two cases with clinicopathological, immunohistochemical and electron microscopic findings. Hum Path, 26: 607–613, 1995.
6.
MitnickPDGoldfarbSSlatopolskyELemannJGrayRWAgusZ: Calcium and phosphate metabolism in tumoral calcinosis. Ann Intern Med92:482–487, 1980.
7.
MozzafarrianGLaffertyFWPearsonOH: Treatment of tumoral calcinosis with phosphorus deprivation. Ann Intern Med77:741–745, 1972.
8.
SlavinREWenJKumarDEvansEB: Familial Tumoral Calcinosis: A clinical, histopathologic, and ultrastructural study with an analysis of its calcifying process and pathogenesis. Am J Surg Path17: 788–802, 1993.
9.
SmackDPNortonSAFitzpatrickJE: Proposal for a pathogenesis based classification of tumoral calcinosis. Int J Derm35:265–271, 1996.
