The breast is a site of choice of the benign myofibroblastic lesions, but only three myofibrosarcomas have been reported, and only one was in the male breast. We report three tumors of the male breast with the features of myofibroblastic differentiation. These tumors comprise a spectrum including two benign neoplasms with a different histologic aspect and one recurrent sarcoma of myofibroblasts with a 10-year follow-up. This is the fourth case to be reported of mammary myofibroblastic sarcoma and the second case in the male breast.
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