The finding of Pacinian corpuscles (PCs) in association with the prostate gland is an anatomical rarity. We present the largest series to date of 23 peri-prostatic PCs from 14 patients identified during routine reporting of radical prostatectomy and cystoprostatectomy specimens with or without pelvic lymph node dissection. The clinicopathological features of this perplexing anatomical structure, including the location, size, shape, immunohistochemical and ultrastuctural findings are thoroughly investigated. We also identify for the first time the clustered appearance of PCs in 2 patients consistent with PC hyperplasia.
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