Malignant transformation of endometriosis is rare, and most cases concern the ovaries, while extraovarian cases are mostly found in the rectovaginal septum. Incisional adenocarcinoma is extremely rare, with only few cases reported in the literature, while their molecular profile remains unknown. Thus, we report on an abdominal wall cesarean section scar endometrioid adenocarcinoma studied by next-generation sequencing and microsatellite instability analysis.
MihailoviciARottenstreichMKovelSWassermannISmorgickNVakninZ. Endometriosis-associated malignant transformation in abdominal surgical scar. Medicine (Baltimore). 2017;96(49):e9136.
4.
GiannellaLSerriMMaccaroniE, et al. Endometriosis-associated clear cell carcinoma of the abdominal wall after caesarean section: a case report and review of the literature. In Vivo (Brooklyn). 2020;34(4):2147-2152.
5.
BedellSChangZBurtCKhalifaMAArgentaPA. Incisional carcinoma of Mullerian origin: a case report and review of literature. Gynecol Oncol Reports. 2020;33:100588.
6.
KobelMRabbanJMcCluggageWShihIHuntsmanDLimD. Endometrioid carcinoma of the ovary. In: WHO Classification of Tumours Female Genital Tumours [Internet]. 5th ed. International Agency for Research on Cancer; 2020. Available from: https://tumourclassification.iarc.who.int/chapters/34
7.
GoodeELBlockMSKalliKR, et al. Dose-Response association of CD8 + tumor-infiltrating lymphocytes and survival time in high-grade serous ovarian cancer. JAMA Oncol. 2017;3(12):e173290.
8.
BenoitLArnouldLCheynelN, et al. Malignant extraovarian endometriosis: a review. Eur J Surg Oncol. 2006;32(1):6-11.
9.
ModesittS. Ovarian and extraovarian endometriosis-associated cancer. Obstet Gynecol. 2002;100(4):788-795.
10.
StewartCHuntsmanDFukunagaMAyhanA. Endometriosis and derived tumours. In: WHO Classification of Tumours Female Genital Tumours [Internet]. 5th ed. International Agency for Research on Cancer; 2020. Available from: https://tumourclassification.iarc.who.int/chapters/34
IshidaGMMotoyamaTWatanabeTEmuraI. Clear cell carcinoma arising in a cesarean section scar. Acta Cytol. 2003;47(6):1095-1098.
13.
LiXYangJCaoDLangJChenJShenK. Clear-Cell carcinoma of the abdominal wall after cesarean delivery. Obstet Gynecol. 2012;120(Part 2):445-448.
14.
WilliamsCPetignatPBelisleADrouinP. Primary abdominal wall clear cell carcinoma: case report and review of literature. Anticancer Res. 2009;29(5):1591-1593.
15.
AustSTiringerDGrimmCStaniJLangerM. Therapy of a clear cell adenocarcinoma of unknown primary arising in the abdominal wall after cesarean section and after hysterectomy. Wien Klin Wochenschr. 2015;127(1–2):62-64.
16.
WangLRambauPFKelemenLE, et al. Nuclear β-catenin and CDX2 expression in ovarian endometrioid carcinoma identify patients with favourable outcome. Histopathology. 2019;74(3):452-462.