Diaphragm disease of small intestine usually presents with nonspecific clinical features. Radiological investigations often fail to differentiate it from small intestinal tumors and inflammatory bowel disease. It is therefore diagnosed on final histology after surgical resection. We hereby report an interesting case of a suspected small bowel tumor later diagnosed as diaphragm disease on histology.
PilgrimSVelchuruVWatersGTsiamisALalR. Diaphragm disease and small bowel enteropathy due to nonsteroidal anti-inflammatory drugs: a surgical perspective. Colorectal Dis. 2011;13:463-466.
2.
SpeedCABrambleMGCorbettWAHaslockI. Non-steroidal anti-inflammatory induced diaphragm disease of the small intestine: complexities of diagnosis and management. Br J Rheumatol. 1994;33:778-780.
3.
ZhaoBSanatiSEltorkyM. Diaphragm disease: complete small bowel obstruction after long-term nonsteroidal anti-inflammatory drugs use. Ann Diagn Pathol. 2005;9:169-173.
4.
MatsuiHShimokawaOKanekoTNaganoYRaiKHyodoI. The pathophysiology of non-steroidal anti-inflammatory drug (NSAID)-induced mucosal injuries in stomach and small intestine. J Clin Biochem Nutr. 2011;48:107-111.
De PetrisGLopezJI. Histopathology of diaphragm disease of the small intestine: a study of 10 cases from a single institution. Am J Clin Pathol. 2008;130:518-525.
7.
SlesserAAWhartonRSmithGVBuchananGN. Systematic review of small bowel diaphragm disease requiring surgery. Colorectal Dis. 2012;14:804-813.
8.
HayashiYYamamotoHTaguchiH. Nonsteroidal anti-inflammatory drug-induced small-bowel lesions identified by double-balloon endoscopy: endoscopic features of the lesions and endoscopic treatments for diaphragm disease. J Gastroenterol. 2009;44(suppl 19):57-63.