Thymomas are tumors with an indolent behavior and long clinical course, usually confined to the anterior mediastinum. Local recurrence is frequent while distant metastases are extremely rare. We report an unusual case of a B2 thymoma with a single renal metastasis The challenge in this case was the frozen section intraoperative diagnosis because of the clinical suspicion of malignant lymphoma. This report also highlights the role of surgical removal of solitary metastases.
VladislavTJainRKAlvarezR. Extrathoracic metastases of thymic origin: a review of 35 cases. Mod Pathol. 2012;25:370-377.
2.
TravisWDBrambillaEMuller-HermelinkHKHarrisCC. World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Lung, Pleura, Thymus and Heart. Lyon, France: IARC Press; 2004.
3.
Bott-KothariTAronBSBejaranoP. Malignant thymoma with metastases to the gastrointestinal tract and ovary: a case report and literature review. Am J Clin Oncol. 2000;23:140-142.
4.
IchinoYObuchiMSukoKIshikawaT. Malignant thymoma with distant metastases: a case report and review of the literature. Jpn J Clin Oncol. 1983;13:733-739.
5.
BerghNPGatzinskyPLarssonSLundinPRidellB. Tumors of the thymus and thymic region: I. Clinicopathological studies on thymomas. Ann Thorac Surg. 1978;25:91-98.
6.
NeedlesBKemenyNUrmacherC. Malignant thymoma: renal metastases responding to cis-platinum. Cancer. 1981;48:223-226.
7.
DemirkiranFBeseTArvasMYilmazOIlvanS. Ovarian metastasis from malignant thymoma. Int J Gynaecol Obstet. 2009;105:176-177.
NirmalaSJanakiMGMalavikaKRishiKS. Invasive thymoma with intraorbital metastases. J Cancer Res Ther. 2009;5:41-42.
10.
KwonGYHongSAHongMEParkESYooJHLeeTJ. Fine needle aspiration biopsy for the diagnosis of thymoma metastatic to the breast: a case report. Acta Cytol. 2010;54(5 suppl):798-802.
11.
YamaguchiTSanoHSuzukiTMakinoHOohashiKOkamotoM. Middle ear metastasis of thymoma. Auris Nasus Larynx. 2012;39:90-93.
12.
OyamaHKitoAMakiHHattoriKNiwaA. Intracranial metastasis of thymoma: report of three cases. No Shinkei Geka. 2011;39:663-668.
13.
ElliottKSBorowskyMEBakdounesKHuangJAbulafiaOLeeYC. Malignant thymoma metastatic to the pelvis: a rare case and considerations for management. Gynecol Oncol. 2005;99:228-231.
