Melanosis coli is a well-known occurrence in colonic biopsies. The condition is, however, reportedly absent in both neoplastic and hyperplastic colonic polyps. Herein, we describe its occurrence in 10 hyperplastic coloniuc polyps, some of which showed melanosis in adjacent biopsied mucosa, and 2 colonic adenomata.
RegitnigPDenkH. Lack of pseudo melanosis coli in colonic adenomas suggests different pathways of apoptotic bodies in normal and neoplastic mucosa. Virchows Arch. 2000;436:588-594.
2.
MalikAHAndrabiSINiayeshM. Pseudo-obstruction with pitch black: a very rare presentation of melanosis coli. Ulster Med J. 2008;77:54-55.
3.
Van WeyenbergSJHoentjenFThunnissenFMulderCJ. Pseudomelanosis coli and adenomatous poyps. J Gastrointestin Liver Dis. 2011;20:233.
4.
ShemeshEBatLNivYNewmanG. Melanosis coli within an adenomatous polypGastrointest Endosc. 1983;29:327-329.
5.
ByersRJMarshPParkinsonDHaboubiNY. Melanosis coli is associated with an increase in colonic epithelial apoptosis and not with laxative use. Histopathology. 1997;30:160-164.
6.
EwingCAKalanMChuckerFOzdemirliM. Melanosis coli involving pericolonic lymph nodes associated with the herbal laxative Swiss Kriss: a rare incidental finding in a patient with colonic adenocarcinoma. Arch Pathol Lab Med. 2004;128:565-567.
7.
Fenoglio-PreiserCNoffsingerAELantzPEStemmermannGNIsaacsonPG, eds. Gastrointestinal Pathology: An Atlas and Text. 3rd ed.Philadelphia, PA: Walters Kluwer/Lippincott Williams & Wilkins; 2009.