Combined Carcinoid Tumor and Squamous Cell Carcinoma of Lung: Expanding the Spectrum of Combined Tumors of Lung

Abstract

Combined lung cancers containing both small cell and non—small cell carcinoma elements are uncommon but well recognized. Lung tumors with neuroendocrine differentiation form a group of histologically distinct tumors with differing clinical behavior ranging from low-grade tumors with good prognosis (typical carcinoid) to intermediate-grade tumors (atypical carcinoid) to high-grade tumors with poor prognosis (small cell carcinoma and large cell neuroendocrine tumors). The authors report clinical findings and pathologic findings in a case of combined carcinoid tumor and squamous cell carcinoma of lung. To the best of the authors’ knowledge, this is the first report of such a case in the peer reviewed literature, thus broadening the spectrum of combined lung tumors.