Follicular dendritic cell (FDC) sarcoma is a rare and probably even underreported entity. Only approximately some 50 cases have been described in the literature,1 the majority of which had a lymph node origin. The authors report a case of FDC sarcoma arising within the soft tissues of the abdominal cavity. As FDC markers are often not routinely included in antibody panels, awareness of this sarcoma is important, as it can be confused with other tumors, especially when occurring extranodally.
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2.
Weiss LM, Grogan TM, Muller-Hermelink HK, et al. Histiocytic and dendritic cell neoplasm: follicular dendritic cell sarcoma. In: Jaffe ES, ed. WHO Classification of Tumours: Tumours of the Haematopoietic and Lymphoid Tissues. Lyon, France: IARC Press; 2001 :278-319.
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Chan AC, Chan KW, Chan JK, et al. Development of follicular dendritic cell sarcoma in hyaline-vascular Castleman's disease of the nasopharynx: tracing its evolution by sequential biopsies. Histopathology. 2001;38:510-518.
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Cheuk W., Chan JK, Shek TW, et al. Inflammatory pseudotumor-like follicular dendritic cell tumor: a distinctive low-grade malignant intra-abdominal neoplasm with consistent Epstein-Barr virus association. Am J Surg Pathol. 2001;25:721-731.
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