AldermanC.P., AllcroftP.D.. Digoxin-itraconazole interaction: possible mechanisms. Ann Pharmacother1997; 31: 438-40.
2.
KartnerN., Evemden-PorelleD., BradleyG., LingV.. Detection of P-glycoprotein in multidrug resistant cell lines by monoclonal antibodies. Nature1985; 316: 820-3.
3.
ThiebautF., TsuruoT., HamadaH., GottesmanM.M., PastanI., WillinghamM.C.. Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues. Proc Natl Acad Sci U S A1987; 84: 7735-8.
4.
SugawaraI., KataokaI., MorishitaY., HamadaH., TsuruoT., ItoyamaS.Tissue distribution of P-glycoprotein encoded by a multidrug-resistant gene as revealed by a monoclonal antibody, MRK 16. Cancer Res1988; 48: 1926-9.
5.
HorioM., ChinK-V, CurrierS.J., GoldenbergS., WilliamsC., PastanI.Transepithelial transport of drugs by the multidrug transporter in cultured Madin-Darby canine kidney cell epithelia. J Biol Chem1989; 264: 14880-4.
6.
TanigawaraY., OkamuraN., HiraiM., YasuharaM., UedaK., KiokaN.Transport of digoxin by human P-glycoprotein expressed in a porcine kidney epithelial cell line (LLC-PK1). J Pharm Exp Ther1992; 263: 840-5.
7.
SchinkelA.H., WagenaarE., van DeemterL., MolC.A.A.M., BorstP.. Absence of the MDR 1a P-glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A. J Clin Invest1995; 96: 1698-705.
8.
de LannoyI.A.M., SilvermanM.. The MDR1 gene product, P-glycoprotein, mediates the transport of the cardiac glycoside, digoxin. Biochem Biophys Res Commun1992; 189: 551-7.
9.
GuptaS., KimJ., GollapudiS.. Reversal of daunorubicin resistance in p388/adr cells by itraconazole. J Clin Invest1991; 87: 1467-9.
10.
ItoS., WoodlandC., KorenG.. Modeling of cellular digoxin transport (abstract). Pharmacologist1997; 39: 114.
11.
ItoS., WoodlandC., KorenG.. Ketoconazole and itraconazole inhibit digoxin transport across renal tubular cell monolayer (MDCK) (abstract). Pediatr Res1995; 37: 77A.
12.
RexJ.. Itraconazole–digoxin interaction (letter). Ann Intern Med1992; 116: 525.
