Recent Advances in Critical Care

American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Crit Care Med 1992; 20: 864–74.

Demling RH . Adult respiratory distress syndrome: Current concepts. New Horizons 1993; 1: 388–401.

Slotman GJ Fisher CJ Bone RC Clemmer TP Metz CA . Detrimental effects of high-dose methylprednisolone sodium succinate on serum concentrations of hepatic and renal function indicators in severe sepsis and septic shock. Crit Care Med 1993; 21: 191–5.

Moncada S Higgs A . The L-arginine nitric oxide pathway. N Engl J Med 1993; 329: 2002–12.

Jobe A . Pulmonary surfactant therapy. N Engl J Med 1993; 328: 861–8.

Tuchschmidt J Fried J Asriz M Rackow E . Elevation of cardiac output and oxygen delivery improves outcome in septic shock. Chest 1992; 102: 216–20.

Shoemaker WC Appel PL Kram HB . Hemodynamic and oxygen transport responses in survivors and nonsurvivors of high risk surgery. Crit Care Med 1993; 21: 977–90.

Moran JL O'Fathartaigh MS Peisach AR Chapman MJ Leppard P . Epinephrine as an inotropic agent in septic shock: A dose-profile analysis. Crit Care Med 1993; 21: 70–7.

Gregory JS Bonfiglio MF Dasta J Reilley TW Townsend MC Flancbaum L . Experience with phenylephrine as a component of the pharmacologic support of septic shock. Crit Care Med 1991; 19: 1395–400.

Martin C Papazian L Perrin G Saux P Gouin F . Norepinephrine or dopamine for the treatment of hyperdynamic septic shock? Chest 1993; 103: 1826–31.

Zarowitz BJ Robert S Peterson EL . Prediction of glomerular filtration rate using aminoglycoside clearance in critically ill medical patients. Ann Pharmacother 1992; 26: 1205–10.

Tholl DA Shikuma LR Miller TQ Woodward JMB Cerra FB Zaske DE . Physiologic response of stress and aminoglycoside clearance in critically ill patients. Crit Care Med 1993; 21: 248–51.

Boucher BA Kuhl DA Fabian TC Robertson JT . Effect of neurotrauma on hepatic drug clearance. Clin Pharmacol Ther 1991; 50: 487–97.

DiPiro JT Hooker KD Sherman JC Gaines MG Wynn JJ . Effect of experimental hemorrhagic shock on hepatic drug elimination. Crit Care Med 1992; 20: 810–5.

Hansen-Flaschen J Cowen J Raps EC . Neuromuscular blockade in the intensive care unit. Am Rev Respir Dis 1993; 147: 234–36.

Carrasco G Molina R Costa J Soler JM Cabre L . Propofol vs. midazolam in short-, medium-, and long-term sedation of critically ill patients. Chest 1993; 103: 557–64.

Wilt JL Minnema AM Johnson RF Rosenblum AM . Torsades de pointes associated with the use of intravenous haloperidol. Ann Intern Med 1993; 119: 391–4.

Segredo V Caldwell JE Matthay MA Sharma ML Gruenke LD Miller RD . Persistent paralysis in critically ill patients after long-term administration of vecuronium. N Engl J Med 1992; 327: 524–8.

Topulos GP . Neuromuscular blockade in adult intensive care. New Horizons 1993; 1: 447–62.

Schuster DP . Stress ulcer prophylaxis: In whom? with what? (editorial) Crit Care Med 1993; 21: 4–6.

Patel R Touchette MA Ben-Menachem T Fogel R Bresalier R Zarowitz BJ . Efficacy and safety of prophylaxis for stress-related gastrointestinal hemorrhage in the medical intensive care unit: A controlled clinical trial (abstract). Pharmacother 1993; 13: 273.

Martin LF Booth FVMCL Karlstadt RG Silverstein JH Jacobs DM Hampsey J Continuous intravenous cimetidine decreases stress-related upper gastrointestinal hemorrhage without promoting pneumonia. Crit Care Med 1993; 21: 19–30.

Driks MR Craven DR Celli BR Manning M Burke RA Garvin GM Nosocomial pneumonia in intubated patients given sucralfate as compared with antacids or histamine type 2 blockers. N Engl J Med 1987; 317: 1376–82.

Pemberton LB Schaeffer N Goehring L Gaddis M Arrighi DA . Oral ranitidine as prophylaxis for gastric stress ulcers in intensive care unit patients: Serum concentrations and cost comparisons. Crit Care Med 1993; 21: 339–42.

Emergency Cardiac Care Committee and Subcommittees, American Heart Association. Guidelines for cardiopulmonary resuscitation and emergency cardiac care. III: Adult advanced cardiac life support. JAMA 1992; 268: 2199–241.