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Hirsch JD . Sublingual morphine sulfate in chronic pain management. Clin Pharm 1984; 3: 585–6.

Pitorak EF Kraus JC . Pain control with sublingual morphine. Am J Hosp Care 1987; 4: 39–41.

Osborne R Joel S Trew D Slevin M . Morphine and metabolite behavior after different routes of morphine administration: Demonstration of the importance of the active metabolite morphine-6-glucuronide. Clin Pharmacol Ther 1990; 47: 12–9.

Weinberg DS Inturrisi CE Reidenberg B Moulin DE Nip TJ Wallenstein S . Sublingual absorption of selected opioid analgesics. Clin Pharmacol Ther 1988; 44: 335–42.

Pannuti F Rossi AP Iafelice G Marraro D Camera P Cricca A . Control of chronic pain in very advanced cancer patients with morphine hydrochloride administered by oral, rectal, and sublingual route: Clinical report and preliminary results on morphine pharmacokinetics. Pharmacol Res Commun 1982; 4: 369–80.

Osborne R Joel S Duncan T Slevin M . Analgesic activity of morphine-6-glucuronide (letter). Lancet 1988; 1: 828.

Scott J Huskisson EC . Graphic representation of pain. Pain 1976; 2: 175–84.

Neuwirth H deKernion JB . Prostate. In: Haskell CM . Cancer treatment. 3rd ed. Philadelphia: Harcourt Brace Jovanovich, 1990: 737–49.

Whitmore WF Jr . Symposium on hormones and cancer therapy; hormone therapy in prostatic cancer. Am J Med 1956; 21: 697–713.

Perez CA Fair WR Ihde DC . Carcinoma of the prostate. In: DeVita VT Jr Hellman S Rosenberg SA . Cancer principles and practice of oncology. 3rd ed. Philadelphia: Lippincott, 1989: 1023–58.

Sonino N . The use of ketoconazole as an inhibitor of steroid production. N Engl J Med 1987; 317: 812–8.

Pont A Williams PL Azhar S Reitz RE Bochra C Smith ER . Ketoconazole blocks testosterone synthesis. Arch Intern Med 1982; 142: 2137–40.

Trachtenberg J Halpern N Pont A . Ketoconazole: A novel and rapid treatment for advanced prostatic cancer. J Urol 1983; 130: 152–3.

Trachtenberg J Pont A . Ketoconazole therapy for advanced prostate cancer. Lancet 1984; 2: 433–5.

Aabo K Kjaer M Hansen HH . High-dose ketoconazole to untreated stage D prostate cancer. Eur J Cancer Clin Oncol 1988; 24: 431–7.

Tapazoglou E Subramanian MG Al-Sarraf M Kresge C Decker DA . High dose ketoconazole therapy in patients with metastatic prostate cancer. Am J Clin Oncol 1986; 9: 369–75.

Pont A . Long-term experience with high dose ketoconazole therapy in patients with stage D₂ prostate carcinoma. J Urol 1987; 137: 902–4.

Witjes FJ Debruyne FMJ Del Moral PF Geboers ADH . Ketoconazole high dose in management of hormonally pretreated patients with progressive metastatic prostate cancer. Urology 1989; 33: 411–5.

Johnson DE Babaian RJ Von Eschenbach AC Wishnow KI Tenney D . Ketoconazole therapy for hormonally refractive metastatic prostate cancer. Urology 1988; 31: 132–4.

Allen JM Kerle DJ Ware H Dobe EA Williams G Bloom SR . Combined treatment with ketoconazole and luteinizing hormone releasing hormone analogue: A novel approach to resistant progressive prostatic cancer. Br Med J 1983; 287: 1766.

Litt MR Bell WR Lepor HA . Disseminated intravascular coagulation in prostatic carcinoma reversed by ketoconazole. JAMA 1987; 258: 1361–2.

Lowe FC Somers WJ . The use of ketoconazole in the emergency management of disseminated intravascular coagulation due to metastatic prostatic cancer. J Urol 1987; 137: 1000–2.

Lowe FC Bamberger MH . Indications for use of ketoconazole in management of metastatic prostatic cancer. Urology 1990; 36: 541–5.

Vanuytsel L Ang KK Vantongelen K Drochmans A Baert L Van Der Schueren E . Ketoconazole therapy for advanced prostatic cancer: Feasibility and treatment results. J Urol 1987; 137: 905–8.