Multiple open and double-blind studies have confirmed the efficacy of ketoconazole in the treatment of pityriasis versicolor. Single-dose (400 mg) or short-course (200 mg/d for five days) therapy may be highly effective for selected patients with pityriasis versicolor. Toxicity seems to be minimal at this dosage.
Get full access to this article
View all access options for this article.
References
1.
FaergemannJFrederikssonT. Tinea versicolor: Some new aspects on etiology, pathogensis, and treatment. Int J Dermatol1982; 21: 8–11.
2.
BorgersMMVan Den BosscheHDe BrabanderM. The mechanism of action of the new antimycotic ketoconazole. Am J Med1983; 74 (suppl B):2–8.
3.
JanssenPSymoensJ. Hepatic reactions during ketoconazole treatment. Am J Med1983; 74 (suppl B):80–5.
4.
BorelliD. Treatment of pityriasis versicolor with ketoconazole. Rev Infect Dis1980; 2: 592–5.
5.
JolliffeDNgaiY. Systemic treatment of tinea versicolor with ketoconazole in forty-four patients. Clin Exp Dermatol1981; 6: 625–8.
6.
UrcuyoFZaiasN. The successful treatment of pityriasis versicolor by systemic keoconazole. J Am Acad Dermatol1982; 6: 24–5.
7.
FaergemannJDjarvL. Tinea veriscolor: Treatment and prophylaxis with ketoconazole. Cutis1982; 30: 542–5,550.
8.
Schewach-MilletMKahanaMLevyAYaron-SchifferOSommerBShalishL. Ketoconazole—an effective treatment for disseminated pityriasis versicolr. Isr J Med Sci1984; 20: 417–9.
9.
HayRMidgeleyG. Short course ketoconazole therapy in pityriasis versicolor. Clin Exp Dermatol1984; 9: 571–3.
10.
SavinR. Systemic ketoconazole in tinea versicolor a double-blind evaluation and 1-year follow up. J Am Acad Dermatol1984; 10: 824–30.
11.
RauschLJacobsP. Tinea versicolor: Treatment and prophylaxis with monthly administration of ketoconazole. Cutis1984; 34: 470–1.
12.
ZaiasN. Pityriasis versicolor with ketoconazole (letter). J Am Acad Dermatol1989; 20: 703–4.
13.
Lake-BakaarGScheuerPSherlockS. Hepatic reactions associated with ketoconazole in the United Kingdom. Br Med J1987; 294: 419–2.