Interstitial nephritis is a rare but serious adverse effect of many drugs and usually is diagnosed by clinical signs and symptoms of hematuria, proteinuria, eosinophilia, fever, azotemia, and rash. Ciprofloxacin is one drug that has been reported to cause interstitial nephritis. Renal toxicities have been reported in less than one percent of the patients receiving ciprofloxacin therapy. Limited documentation of this adverse effect exists in the literature. This article describes a patient with suspected ciprofloxacin-induced interstitial nephritis.
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References
1.
TollLLLeeMSharifiR. Cefoxitin-induced interstitial nephritis. South Med J1987; 80: 274–5.
2.
NessiRBonoldiGLRedaelliB. DI FILIPPO G. Acute renal failure after rifampin: A case report and survey of the literature. Nephron1976; 16: 148–59.
3.
PuseyLDSaltissiDBloodworthLRainfordDJChristieJL. Drug associated IN: Clinical and pathological features and responses to high dose steroid therapy. Q J Med1983; 52: 194–211.
4.
BallP. Ciprofloxacin: An overview of adverse experiences. J Antimicrob Chemother1986; 18: 187–93.
5.
RippelmeyerDJSynhavskyDJ. Ciprofloxacin and allergic interstitial nephritis (letter). Ann Intern Med1988; 109: 170.
