We report evidence that sublingual Clonidine may be effective in the treatment of hypertension in the patient unable to take oral medication. Four cases are presented illustrating the utility of this regimen; few side effects were observed. Sublingual Clonidine may be a useful addition to the treatment of the hypertensive patient because of its apparent effectiveness, simplicity, and safety.
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2.
HanssonLHunyorSNJuliusSHooblerSW. Blood pressure crises following withdrawal of Clonidine with special reference to arterial and urinary catecholamine levels and suggestions for acute management. Am Heart J1973; 85: 605–10.
3.
TschollarWBelzGG. Sublingual Captopril and hypertensive crises. Lancet1985; 2: 34–5.
4.
Hauger-KleveneJH. Treatment of Clonidine rebound syndrome with sublingual Captopril. N Engt J Med1986; 314: 181–2.
5.
BeerNGallegosICohenA. klein n, sonnenblicke-frishman w. Efficacy of sublingual nifedipine in the acute treatment of systemic hypertension. Chest1981; 79: 571–4.
