A case is presented that describes the use of an intravenous morphine infusion to treat severe pain in an outpatient setting. The patient had severe pain secondary to tumor involvement of the brachial plexus. Morphine was administered as a concentrated solution (50 mg/ml), using an autosyringe (model AS-2F) via a Hickman catheter. The dose was titrated to pain relief. A dose of 200–250 mg/h was required.
LipmanAG. Drug therapy in cancer pain. Cancer Nurs1980; 3: 39–46.
2.
HolmesAH. Morphine IV infusions for chronic pain (letter). Drug Intell Clin Pharm1978; 12: 556–7.
3.
ChurchJJ. Continuous narcotic infusions for relief of postoperative pain. Br Med J1979; 1: 977–9.
4.
EnsworthS. Morphine IV infusion for chronic pain (letter). Drug Intell Clin Pharm1979; 13: 297.
5.
RutterPCMurphyFDudleyHAF. Morphine: Controlled trial of different methods of administration for postoperative pain. Br Med J1980; 1: 12–3.
6.
KowolenkoM. An additional comment on morphine IV infusion (letter). Drug Intell Clin Pharm1980; 14: 296–7.
7.
MiserAWMiserJSClarkBS. Continuous intravenous infusion of morphine sulfate for control of severe pain in children with terminal malignancy. J Pediatr1980; 96: 930–2.
8.
FraserDG. Intravenous morphine infusion for chronic pain. Ann Intern Med1980; 93: 781–2.
9.
CohenMR. From your newsletter: Morphine infusion protocol. Hosp Pharm1981; 16: 296–7.
10.
BjeletichJHickmanRO. The Hickman indwelling catheter. Am J Nurs1980; 80: 62–5.
11.
GravesDABatenhorstRLBennettRLMorphine requirements using patient controlled analgesia: Influence of diural variation and morbid obesity. Clin Pharm1983; 2: 49–53.
12.
SchmidtAMWilliamsD. The Hickman catheter: Sending your patient home safely. RN1982; 45: 57–61.
13.
LokichJBotheAFineNPerriJ. The delivery of cancer chemotherapy by constant venous infusion. Cancer1982; 50: 2731–5.
14.
CampbellCFMasonJBWeilerJM. Continuous subcutaneous infusion of morphine for the pain of terminal malignancy. Ann Intern Med1983; 98: 51–2.
15.
SingerLJ. Morphine in control of severe pain (letter). Drug Intell Clin Pharm1982; 16: 883.
