van RossumJMvan GinnekenCAMHendersonPTKetelaarsHCJVreeTB. Pharmacokinetics of biotransformation. In: van RossumJM, ed. Kinetics of drug action. Berlin: Springer Verlag, 1977: 124–67.
2.
HwangSKwanKCAlbertKS. Bioavailability assessment of a drug and a metabolite undergoing reversible metabolism. 26th American Pharmaceutical Association National Meeting, April 21–26, 1979, Anaheim, CA (abstract 35).
3.
VreeTBHeksterYABaarsAMDamsmaJEvan der KleijnE. Pharmacokinetics of sulphamethoxazole and renal excretion of sulphamethoxazole and its metabolite N4-acetylsulphamethoxazole. Clin Pharmacokinet1978; 3: 319–29.
4.
VreeTBHeksterYADamsmaJEvan der KleijnEO'ReillyWJ. Pharmacokinetics of N1-acetyl- and N4-acetyl-sulphamethoxazole in man. Clin Pharmacokinet1979; 4: 310–9.
5.
WeberWWRadtkeHETannenRH, Extrahepatic N-acetyltransferases and N-deacetylases. In: GramTE, ed. Extrahepatic metabolism of drugs and other foreign compounds. Lancaster, UK: MTP Press Ltd, 1980: 493–532.
6.
DuttonGJBurchellB. Newer aspects of glucuronidation. In: BridgesJWChasseaudLF, eds. Progress in drug metabolism. Bristol, UK: John Wiley, 1977: 1–70.
7.
HeksterYAVreeTB. Clinical pharmacokinetics of sulphonamides and their N4-acetyl derivatives. Antibiot Chemother1981: In press.
8.
GreenblattDJWooEAllenMDOrsulakPJShaderRI. Rapid recovery from massive diazepam overdose. JAMA1978; 240: 1872–4.
9.
KrebsHASykesWOBartleyWC. Acetylation and deacetylation of the p-amino group of sulphonamide drugs in animal tissue. Biochem J1947; 41: 622–30.
10.
BaethkeRGoldeGGahlG. Sulfamethoxazole/trimethoprim: Pharmacokinetic studies in patients with chronic renal failure. Eur J Clin Pharmacol1972; 4: 223–40.
11.
VreeTBHeksterYADamsmaJEvan DalenRHafkenscheidJCMFriesenWT. Renal excretion of sulfamethoxazole and its metabolite N4-acetylsulfamethoxazole in patients with impaired kidney function. Ther Drug Monitoring1981; 3: 129–35.
12.
RueliusHWTioCOKnowlesJAMcHughSLSchillingsRTSisenwineSF. Diastereoisomeric glucuronides of oxazepam. Isolation and stereoselective enzymic hydrolysis. Drug Metab Dispos1979; 7: 40–3.
13.
van der KleijnEVreeTBBaarsAMWijsmanREdmundsLCKnopHJ. Factors influencing the activity and fate of benzodiazepines in the body. Br J Clin Pharmacol1981; 11: S85–98.
14.
GreenblattDJShaderRIFrankeK. Pharmacokinetics and bioavailability of intravenous, intramuscular and oral lorazepam in humans. J Pharm Sci1979; 68: 57–63.
15.
VreeTBHeksterYABaakmanM. Farmaco-kinetische kriteria die bepalend kunnen zijn voor de keuze van een sulfonamide. J Drug Res1982: In press.
16.
VreeTBHeksterYABaakmanM. Rate constants of acetylation and deacetylation of some sulphonamide derivatives. In: Proceedings of the 12th International Congress of Chemotherapy, Florence, Italy: 1981. Washington, DC: ASM, 1981: In press.