Zomepirac (Zomax®,McNeil Pharmaceutical)

FDA-approved package insert, zomepirac sodium (Zomax®), McNeil Pharmaceutical, Spring House, PA 19477.

Pruss TP , Gardocki JF , Taylor RJ , Muschek LD . Evaluation of the analgesic properties of zomepirac. J Clin Pharmacol 1980; 20: 216–22.

O'Brien CP , Minn FL . Evaluation for withdrawal symptoms following chronic zomepirac administration. J Clin Pharmacol 1980; 20: 397–400.

Ng KT , Snyderman T. Determination of zomepirac in plasma by high-pressure liquid chromatography. J Chromatogr 1979; 178: 241.

Nayak RK , Ng KT , Gottlieb S , Plostnieks J. Zomepirac kinetics in healthy males. Clin Pharmacol Ther (in press).

Muschek LD , Grindel JM . Review of the pharmacokinetics and metabolism of zomepirac in man and animals. J Clin Pharmacol 1980; 20: 223–9.

O'Neill PJ , Yorgay KA , Migdaloff BH , Gussin RZ . Renal handling of zomepirac in the rat. J Pharmacol Exp Ther 1979; 209: 366–70.

Cooper SA . Efficacy of zomepirac in oral surgical pain. J Clin Pharmacol 1980; 20: 230–42.

Lasagna L. Analgesic methodology: a brief history and commentary. J Clin Pharmacol 1980; 20: 373–6.

Baird AM , Turek D. Comparison of zomepirac, APC with codeine, codeine, and placebo in the treatment of moderate and severe postoperative pain. J Clin Pharmacol 1980; 20: 243–9.

Forrest WH . Oral zomepirac and intramuscular morphine in postoperative pain. J Clin Pharmacol 1980; 20: 259–60. This study also reported in: Forrest WH, Jr. Orally administered zomepirac and parenterally administered morphine. JAMA 1980; 244: 2298-302.

Wallenstein SL , Rogers A , Kaiko RF , Heidrich G , Houde RW . Relative analgesic potency of oral zomepirac and intramuscular morphine in cancer patients with postoperative pain. J Clin Pharmacol 1980; 20: 250–8.

de Andrade JR , Honig S , Ciccone WJ , Leffall L. Clinical comparison of zomepirac with pentazocine in the treatment of postoperative pain. J Clin Pharmacol 1980; 20: 292–7.

Elbaz JS , Bernard A. A controlled repeat-dose comparison of zomepirac and clometacin in pain after plastic surgery. J Clin Pharmacol 1980; 20: 303–8.

Messer RH , Vaughn R , Harbert G. Clinical evaluation of zomepirac and APC with codeine in the treatment of postpartum episiotomy pain. J Clin Pharmacol 1980; 20: 279–84.

Stambaugh JE , Tejada F , Trudnowski RJ . Double-blind comparisons of zomepirac and oxycodone with APC in cancer pain. J Clin Pharmacol 1980; 20: 261–70.

Mayer TG , Ruoff GE . Clinical evaluation of zomepirac in the treatment of acute orthopedic pain. J Clin Pharmacol 1980; 20: 285–91.

McMillen JI , Urbaniak JR , Boas R. Treatment of chronic orthopedic pain with zomepirac. J Clin Pharmacol 1980; 20: 385–91.

Andelman S , Levin J , Simson J , Amadio P , Wenger M. A double-blind crossover comparison of zomepirac and placebo in pain secondary to osteoarthritis of the knee. J Clin Pharmacol 1980; 20: 364–70.

Ruoff GE , Andelman SY , Cannella JJ . Long-term safety of zomepirac: a double-blind comparison with aspirin in patients with osteoarthritis. J Clin Pharmacol 1980; 20: 377–84.

Diamond S. Zomepirac in the symptomatic treatment of muscle contraction headache. J Clin Pharmacol 1980; 20: 298–302.

Johnson PC . A comparison of the effects of zomepirac and aspirin on fecal blood loss. J Clin Pharmacol 1980; 20: 401–5.

Johnson PC . The effect of zomepirac on red blood cell survival and immune system. J Clin Pharmacol 1980; 20: 406–8.

Mielke CH , Kahn SB , Muschek LD , Tighe JJ , Ng KT , Minn FL . Effects of zomepirac on hemostasis in healthy adults and on platelet function in vitro. J Clin Pharmacol 1980; 20: 409–17.

Honig S. Preliminary report: long-term safety of zomepirac. J Clin Pharmacol 1980; 20: 393–6.

Minn FL , Zinny MA . Zomepirac and warfarin: a clinical study to determine if interaction exists. J Clin Pharmacol 1980; 20: 418–21.