Ticarcillin and Carbenicillin

Personal Communication, Beecham Laboratories.

Ervin R. F. Bullock W. E. : Clinical and Pharmacological Studies of Ticarcillin in Gram-Negative Infections, Antimicrob. Agents Chemother. 9: 94–101 (Jan.) 1976.

Parry M. F. Neu H. C. : Pharmacokinetics of Ticarcillin in Patients with Abnormal Renal Function, J. Infect. Dis. 133: 46–49 (Jan.) 1976.

Neu H. C. Winshell E. B. : Semisynthetic Penicillin 6-[D(−)-α-Carboxy-3-Thenylacetamide] Penicillinic Acid Active Against Pseudomonas in Vitro, Appl. Microbiol. 21: 66–79 (Jan.) 1971.

Lynn B. : Administration of Carbenicillin and Ticarcillin - Pharmaceutical Aspects, Eur. J. Cancer 9: 425–433 (June) 1973.

Prior R. B. Warner J. F. : Morphological Alteration of Pseudomonas aeruginosa by Ticarcillin: A Scanning Electron Microscope Study, Antimicrob. Agents Chemother. 6: 853–855 (Dec.) 1974.

Turck M. Petersdorf R. G. : Antimicrobial Therapy, Kagan B. M. , second edition, p. 16, 1974.

Parry M. F. Neu H. C. : Comparison and Evaluation of Ticarcillin and Carbenicillin Using Disk Diffusion Methods, Antimicrob. Agents Chemother. 9: 625–632 (Apr.) 1976.

Sutherland R. : α-Carboxy-3-Thienylmethyl-penicillin (BRL2288) A New Semisynthetic Penicillin: In Vitro Evaluation, Antimicrob. Agents Chemother. 10: 390–395, 1970.

Neu H. C. Winshell E. B. : In Vitro Studies of a Semisynthetic Penicillin, 6-[D-(−)-α-Carboxy-3-Thienylacetamide] Penicillinic Acid (BBL 2288), Active Against Pseudomonas, Antimicrob. Agents Chemother. 10: 385–389, 1970.

Adler J. L. : Susceptibility of Proteus Species and Pseudomonas aeruginosa to Penicillins and Cephalosporins, Antimicrob. Agents Chemother. 10: 63–67, 1970.

Eickhoff T. C. Ehaet J. M. : Comparative Activity In Vitro Of Ticarcillin, BL-P1654, and Carbenicillin, Antimicrob. Agents Chemother. 10: 241–244 (Aug.) 1976.

Kalkani E. Marketos N. : Comparative In Vitro Evaluation of the Effects of Ticarcillin and Carbenicillin upon Pseudomonas aeruginosa, Antimicrob. Agents Chemother. 9: 89–90 (Jan.) 1976.

Bodey G. P. Deerhake B. : In Vitro Studies of α-Carboxy-3-Thienylmethyl Penicillin, A New Semisynthetic Penicillin, Appl. Microbiol. 21: 61–65 (Jan.) 1971.

Wald E. R. : BL-P1654, Ticarcillin and Carbenicillin: In Vitro Comparison Alone and in Combination with Gentamicin Against Pseudomonas aeruginosa, Antimicrob. Agents Chemother. 7: 336–340 (Mar.) 1975.

Parry M. F. Neu H. C. : Ticarcillin for Treatment of Serious Infections with Gram-Negative Bacteria, J. Infect. Dis. 134 (X): 476–485 (Nov.) 1976.

Marks M. I. : Carbenicillin: A Clinical and Laboratory Evaluation, Ann. Intern. Med. 73: 179–187 (Aug.) 1970.

Neu H. C. : B-Lactamase Production by Pseudomonas aeruginosa, Antimicrob. Agents Chemother. 10: 534–538, 1970.

Legakis N. J. Papavassiliou J. : In Vitro Activity of Ticarcillin, Carbenicillin, and Ampicillin Against Some Gram-Negative Bacilli, J. Antibiot. 28: 912–919 (Nov.) 1975.

Klastersky J. : Empiric Therapy for Cancer Patients: Comparative Study of Ticarcillin-Tobramycin, Ticarcillin-Cephalothin, and Cephalothin-Tobramycin, Antimicrob. Agents Chemother. 7: 640–645 (May) 1975.

Hoffman T. A. Bullock W. E. : Carbenicillin Therapy of Pseudomonas and Other Gram-Negative Bacillary Infections, Ann. Intern. Med. 73: 165–171 (Aug.) 1970.

Ticar® (Sterile Ticarcillin Disodium) Hosp. Formul. Inf., Beecham Laboratories, 1976.

Geopen® (Sterile Disodium Carbenicillin) Roerig package insert (May) 1975.

Davies M. : Interactions of Carbenicillin and Ticarcillin with Gentamicin, Antimicrob. Agents Chemother. 7: 431–434 (Apr.) 1975.

Weibert R. : Carbenicillin Inactivation of Aminoglycosides In Patients with Severe Renal Failure, Trans. Am. Soc. Artif. Intern. Organs Vol. XXII: 439–443, 1976.

Rodriguez V. : Ticarcillin Therapy of Infections, Antimicrob. Agents Chemother. 4: 427–431 (Oct.) 1973.

Bodey G. R. : Infections in Cancer Patients, Concer Treat. Rev. 2: 89–128 (Mar.) 1975.

Wise R. : Administration of Ticarcillin, a New Anti-Pseudomonal Antibiotic in Patients Undergoing Dialysis, Antimicrob. Agents Chemother. 5: 119–120 (Feb.) 1974.

Klastersky J. Daneau D. : Comparison between Carbenicillin and (BRL 2288), A New Semisynthetic Penicillin Active Against Pseudomonas Aeruginosa, Ther. Res. 14: 503–509 (Aug.) 1972.

Libke R. D. : Ticarcillin vs Carbenicillin Clinical Pharmacokinetics, Clin. Pharmacol. Ther. 17: 441–446 (Feb.) 1975.

Rodriguez V. : Clinical Pharmacology of Ticarcillin (α-Carboxy-3-Thienylmethyl Penicillin, BRL-2288), Antimicrob. Agents Chemother. 4: 31–36 (July) 1973.

Sutherland R. Wise P. J. : α-Carboxy-3-Thienylmethyl Penicillin (BRL 2288), a New Semisynthetic Penicillin: Absorption and Excretion in Man, Antimicrob. Agents Chemother. 10: 402–406, 1970.

Neu H. C. Garvey G. : Comparative in Vitro Activity and Clinical Pharmacology of Ticarcillin and Carbenicillin, Antimicrob. Agents Chemother. 8: 457–462 (Oct.) 1975.

Cole M. : Metabolism of Penicillin to Penicillinic Acids and 6-Aminopenicillinic Acid in Man and Its Significance in Assessing Penicillin Absorption, Antimicrob. Agents Chemother. 3: 463–468 (Apr.) 1973.

Hoffman T. A. : Pharmacodynamics of Carbenicillin in Hepatic and Renal Failure, Ann. Intern. Med. 73: 173–178 (Aug.) 1970.

Latos D. L. : Carbenicillin Therapy in Patients with Normal and Impaired Renal Function, Clin. Pharmacol. Ther. 17: 692–700 (Mar.) 1975.

Barza M. : Extraction of Antibiotics from the Circulation by Liver and Kidney: Effect on Probenicia, J. Infect. Dis. 131: 586–597 (May) 1975.

Fishman R. A. : Blood-Brain and CSF Barriers to Penicillin and Related Organic Acids, Arch. Neurol. 15: 113–124 (Aug.) 1966.

MacFarlane D. M. McCarron M. M. : Anaphylactic Shock and Anaphylactoid Reaction, Drug Intell. Clin. Pharm. 7: 394–405 (Sept.) 1973.

Brown C. H. III : The Hemostatic Defect Produced by Carbenicillin, N. Engl. J. Med. 291: 265–270 (Aug.) 1974.

Waisbred B. A. : Carbenicillin and Bleeding, J. Am. Med. Assoc. 217: 1243 (Aug.) 1971.

Brown C. H. III : Study of the Effects of Ticarcillin on Blood Coagulation and Platelet Function, Antimicrob. Agents Chemother. 7: 652–657 (May) 1975.

Carbenicillin Disodium, American Hospital Formulary Service, ASHP Vol. 1 8: 12–16 (Jan.) 1974.

Parry M. F. : Treatment of Pulmonary Infection in Patients with Cystic Fibrosis: A Comparative Study of Ticarcillin and Gentamicin, J. Pediatr. 90: 144–148 (Jan.) 1977.