Ganciclovir-Induced Bullae Formation Secondary to Extravasation in a Patient Being Treated for Cytomegalovirus Retinitis

Ganciclovir injection, 2mg/ml (500mg/250mL) [package insert]. Lenoir, NC: Exela Pharma Sciences, LLC; 2017.

Marcollo Pini A Kerl K Kamarachev J French L Hofbauer G . Interstitial granulomatous drug reaction following intravenous ganciclovir. Br J Dermatol. 2008;158:1391-1393. doi:10.1111/j.1365-2133.2008.08560.x

Naranjo CA Busto U Sellers EM et al . A method for estimating the probability of adverse drug reactions. Clin Pharmacol Ther. 1981;30:239-245. doi:10.1038/clpt.1981.154

Buck ML Vittone SB Zaglul HF. Vesicular eruptions following acyclovir administration. Ann Pharmacother. 1993;27:1458-1459. doi:10.1177/106002809302701208

Armingaud P Arsac P Kerdraon R Esteve E. Localized bullous eruption after intravenous injection of acyclovir: toxic or immunoallergic mechanism? Ann Dermatol Venereol. 2000;127:496-498. doi:AD-06-2000-127-5-0151-9638-101019-ART77