Are Dental Maturation,Skeletal Maturation,and Chronological Age Associated With Complete Cleft Lip and Palate?

Abstract

Objective:

The relationship between dental and skeletal development levels was determined in individuals with cleft lip and palate and a control group comprising individuals without cleft lip and palate.

Design:

Retrospective, cross-sectional study.

Setting:

A university clinic specializing in orthodontic and pedodontic care.

Patients:

A total of 198 patients with cleft lip and palate (99 females, 11.66 ± 2.36 years; 99 males, 12.44 ± 2.33 years) and 198 patients without cleft lip and palate (99 females, 11.88 ± 2.26 years; 99 males, 12.99 ± 2.25 years).

Interventions:

None.

Main Outcome Measures:

The Demirjian method and cervical vertebra maturation method were used to evaluate panoramic and lateral cephalometric radiographs, respectively. The Fishman maturation predictors were determined from hand-wrist radiographs.

Results:

Statistically significant correlations were found between the chronological age and the dental age in both the groups (P < .05). Significant correlations between skeletal maturation indicators and dental maturation indicators were observed in both groups and sexes (P < .05), with a stronger correlation among teeth with incomplete dental maturation. Dental age was found to be significantly lower (female, P = .001; male, P = .001) in individuals with cleft lip and palate (female, 11.71 ± 2.58 years; male, 12.51 ± 2.62 years) compared to those in the control group (female, 12.95 ± 2.47 years; male, 13.64 ± 2.37 years).

Conclusions:

A high correlation between the results of the evaluated radiographic methods and chronological age supports their use for accurate age estimation in the patients with cleft lip and palate.

Keywords

cleft lip and palate dental age skeletal maturation dental maturation chronological age age estimation

Get full access to this article

View all access options for this article.

References

Aduss

. Craniofacial growth in complete unilateral cleft lip and palate. Angle Orthod. 1971;41(3):202–213.

Altunhan

Annagur

Konak

Ertugrul

Ors

Koc

The incidence of congenital anomalies associated with cleft palate/cleft lip and palate in neonates in the Konya region, Turkey. Br J Oral Maxillofac Surg. 2012;50(6):541–544.

Bacetti

Franchi

McNamara

Jr . An improved version of the cervical vertebral maturation (CVM) method for the assessment of mandibular growth. Angle Orthod. 2002;72(4):316–323.

Bagattoni

D’Alessandro

Gatto

Piana

. Applicability of Demirjian’s method for age estimation in a sample of Italian children with Down syndrome: a case-control retrospective study. Forensic Sci Int. 2019;298(1):336–340.

Bindayel

Alsultan

Hayek

Almoammer

. Comparison between chronological age and dental ages of Saudi patients with cleft lip and palate. J Contemp Dent Pract. 2019,20(5):603–608.

Burstone

. Process of maturation and growth prediction. Am J Orthod Dentofacial Orthop. 1963;49(12):907–919.

Cunha

Cevidanes

Sant’Anna

Guedes

Luiz

McNamara

Franchi

Ruellas

ACO

. Staging hand-wrist and cervical vertebrae images: a comparison of reproducibility. Dentomaxillofac Radiol. 2018;47(5):20170301.

Demirjian

Buschang

Tanguay

Patterson

. Interrelationships among measures of somatic, skeletal, dental, and sexual maturity. Am J Orthod. 1985;88(5):433–438.

Demirjian

Goldstein

. New systems for dental maturity based on seven and four teeth. Ann Hum Bio. 1976;3(5): 411–421.

10.

Demirjian

Goldstein

Tanner

. A new system of dental age assessment. Hum Biol. 1973;45(2):211–227.

11.

Fang

Fan

Jiang

Qing

Wenlin

Zhonghui

Xiaolin

. Relationship between dental calcification of mandibular teeth and cervical vertebrae maturity in patients with unilateral complete cleft lip and palate [published online April 02, 2020]. Oral Radiol. 2020. doi:10.1007/s11282-020-00433-2

12.

Fishman

. Chronological versus skeletal age, an evaluation of craniofacial growth. Angle Orthod. 1979;49(3):181–189.

13.

Flores-Mir

Nebbe

Major

. Use of skeletal maturation based on hand-wrist radiographic analysis as a predictor of facial growth: a systematic review. Angle Orthod. 2004;74(1):118–124.

14.

Gorlin

Cohen

Jr Hennekam

. Syndromes of the Head and Neck. Oxford University Press; 2001.

15.

Green

. The interrelationships among height, weight and chronological, dental and skeletal ages. Angle Orthod. 1961;31(3):189–193.

16.

Greulich

Pyle

. Radiographic Atlas of Skeletal Development of the Hand and Wrist. Stanford University Press; 1959.

17.

Harris

Hullings

. Delayed dental development in children with isolated cleft lip and palate. Arch Oral Biol. 1990;35(6):469–473.

18.

Harris

Weinstein

Poole

. Predicting adult stature: a comparison of methodologies. Ann Hum Biol. 1980;7(3):225–234.

19.

Hassel

Farman

. Skeletal maturation evaluation using cervical vertebrae. Am J Orthod Dentofacial Orthop. 1995;107(1):58–66.

20.

Heidbüchel

Kuijpers-Jagtman

Ophof

Van Hooft RJ . Dental maturity in children with a complete bilateral cleft lip and palate. Cleft Palate Craniofac J. 2002;39(5):509–512.

21.

Huyskens

Katsaros

Van’t Hof

Kuijpers-Jagtman

. Dental age in children with a complete unilateral cleft lip and palate. Cleft Palate Craniofac J. 2006;43(5):612–615.

22.

Kirzioglu

Ceyhan

. Accuracy of different dental age estimation methods on Turkish children. Forensic Sci Int. 2012;216(1-3):61–67.

23.

Kirzioglu

Ceyhan

Bayraktar

. Dental age estimation by different methods in patients with amelogenesis imperfecta. Forensic Sci Int. 2019;298:341–344.

24.

Lamparski

. Skeletal Age Assessment Utilizing Cervical Vertebrae. [master’s thesis]. University of Pittsburgh, Pittsburgh; 1972.

25.

Lewis

Garn

. The relationship between tooth formation and other maturational factors. Angle Orthod. 1960;30(2):70–77.

26.

Litsas

Athanasiou

Papadopoulos

Ioannidou-Marathiotou

Karagiannis

. Dental calcification stages as determinants of the peak growth period. J Orofac Orthop. 2016;77(5):34–49.

27.

Macha

Lamba

Avula

JSS

Muthineni

Margana

PGJS

Chitoori

. Estimation of correlation between chronological age, skeletal age and dental age in children—a cross-sectional study. J Clin Diagn Res. 2017;11(9):ZC01–ZC04.

28.

Malot-Steinberg

. Prévision de l’éruption dentaire. Revue d’Orthopédie Dento-Faciale. 1978;12(3):233–242.

29.

Mossey

Catilla

. Global Registry and Database on Craniofacial Anomalies: Report of a WHO Registry Meeting on Craniofacial Anomalies; 2006.

30.

Olze

Bilang

Schmidt

Wernecke

Geserick

Schmeling

. Validation of common classification systems for assessing the mineralization of third molars. Int J Legal Med. 2005;119(1):22–26.

31.

Proffit

Fields

Jr Sarver

. Contemporary Orthodontics. 5 ed. Elsevier; 2012.

32.

Rai

Saha

Yadav

Tripathi

Grover

. Dental and skeletal maturity—a biological indicator of chronologic age. J Clin Diagn Res. 2014;8(9):ZC60–ZC64.

33.

Sağlam

AMŞ

Gazilerli

. The relationship between dental and skeletal maturity. J Orofac Orthop. 2002;63(6):454–462.

34.

Santoro

De Donnoa

Marrone

Campobasso

Introna

. Forensic age estimation of living individuals: a retrospective analysis. Forensic Sci Int. 2009;193(1-3):129. e1-e4.

35.

Uysal

Ramoglu

Basciftci

Sari

. Chronologic age and skeletal maturation of the cervical vertebrae and hand-wrist: is there a relationship? Am J Orthod Dentofacial Orthop. 2006;130(5):622–628.

36.

Uysal

Sari

Ramoglu

Basciftci

. Relationships between dental and skeletal maturity in Turkish subjects. Angle Orthod. 2004;74(5):657–664.

37.

Van Dyck

Cadenas Llano

PMD

Willems

Verdonck

. Dental development in cleft lip and palate patients: a systematic review. Forensic Sci Int. 2019;300:63–74.