Data Linkage: Cleft Live-Birth Prevalence and Hospitalizations in Western Australia: 1980 to 2016

Abstract

Objective:

To provide information on live-birth prevalence and hospitalizations, including anxiety and depression, for cleft lip and/or palate (CL/P) in Western Australia (WA), using live-birth data 1980 to 2015.

Design:

Retrospective data linkage.

Setting:

Tertiary hospital.

Patients:

Cleft cohort consisted of people live-born with CL/P in WA between 1980 and 2015, and a gender and age-matched control group.

Measures:

Live-birth prevalence for CL/P by year. Hospital event counts, event ages, and length of stay (LOS) days by 18 diagnosis groups and 4 birth year categories between the cleft cohort and control group, and between cleft types. Count of events per alive persons per calendar year, and relative risk for proportions of persons in the cleft cohort and control group by diagnosis group.

Results:

Live-birth prevalence for CL/P was 19.7 per 10 000 (1 in 522). The cleft cohort had significantly higher event counts, lower event ages, and higher LOS days than the control group. Cleft lip and palate had significantly higher event counts, lower event ages, and higher LOS days than cleft lip or cleft palate only. There were 2 significant differences for anxiety or depression between the cleft cohort and control group, lower event ages, and higher LOS days in 1990s birth year category.

Conclusions:

This study provides a cleft data reference for WA. Live-birth prevalence for all clefts and by cleft type offers an appropriate method for estimating service utilization and provision. Patients with cleft accessed hospital services more frequently, at an earlier age, with higher LOS days than the control group.

Keywords

cleft lip and palate live-birth prevalence hospitalizations Western Australia data linkage

Get full access to this article

View all access options for this article.

References

ABS 2016 Census Quick Stats. Australian bureau of statistics. 2017. Accessed July 16, 2019. https://quickstats.censusdata.abs.gov.au/census_services/getproduct/census/2016/quickstat/5?Opendocument

ABS 2014-15 National Health Survey: First Results. 2017. Accessed October 01, 2019. https://www.abs.gov.au/ausstats/abs@.nsf/Lookup/by%20Subject/4364.0.55.001∼2014-15∼Main%20Features∼Mental%20and%20behavioural%20conditions∼32

Australian Consortium for Classification Development. The International Statistical Classification of Diseases and Related Health Problems, Tenth Revision, Australian Modification (ICD-10-AM/ACHI/ACS). 10th ed. Independent Hospital Pricing Authority; 2017.

British Paediatric Association. British Paediatric Association Classification of Diseases, (successor to the Cardiff diagnostic classification): A Paediatric Supplement Compatible With the Ninth Revision of the WHO International Classification of Diseases. British Paediatric Association; 1979.

Bell

Nassar

Turner

Raynes-Greenow

. Hospitalizations up to adulthood for children born with orofacial clefts. J Paediatr Child Health. 2015;52(4):441–448. doi:10.1111/jpc.13024

Birnbaum

Ludwig

Reutter

Herms

Steffens

Rubini

Baluardo

Ferrian

De Assis

Alblas

, et al. Key susceptibility locus for non syndromic cleft lip with or without cleft palate on chromosome 8q24. Nat Genet. 2009;41(4):473–477.

Boulet

Grosse

Honein

Correa-Villasenor

. Children with orofacial clefts: health-care use and costs among a privately insured population. Public Health Rep. 2009;124(3):447–453.

Cassell

Meyer

Daniels

. Health care expenditures among Medicaid enrolled children with and without orofacial clefts in North Carolina, 1995-2002. Birth Defect Res. 2008;82(11):785–794.

Department of Health. Health conditions: genetic conditions 2017. 2018. Accessed December 23, 2018. https://healthywa.wa.gov.au/Articles/F_I/Genetic-conditions

10.

Fitzsimons

Copley

Deacon

Van der Meulen

. Hospital care of children with a cleft in England. Arch Dis Child. 2013;98(12):970–974.

11.

Foo

Sampson

Roberts

Jamieson

David

. General health-related quality of life and oral health impact among Australians with cleft compared with population norms; age and gender differences. Cleft Palate Craniofac J. 2012;49(4):406–413. doi:10.1597/10-126

12.

Hunt

Burden

Hepper

Stevenson

Johnston

. Self-reports of psychosocial functioning among children and young adults with cleft lip and palate. Cleft Palate Craniofac J. 2006;43(5):598–605. doi:10.1597/05-080

13.

International Perinatal Database of Typical Oral Clefts Working Group. Prevalence at birth of cleft lip with or without cleft palate: data from the international perinatal database of typical oral clefts (IPDTOC). Cleft Palate Craniofac J. 2011;48(1):66–81. doi:10.1597/09-217

14.

Kilpatrick

Jacoby

Slack-Smith

. Description of total population hospital admissions for cleft lip and/or palate in Australia. BMC Oral Health. 2015;15:156.

15.

Mani

Carlsson

Marcusson

. Quality of life varies with gender and age among adults treated for unilateral cleft lip and palate. Cleft Palate Craniofac J. 2010;47(5):491–498.

16.

Mason

Kirby

Sever

Langlois

. Prevalence is the preferred measure of the frequency of birth defects. Birth Defects Research Part A: Clinical and Molecular Teratology, 2005;73: 689–691. https://doi.org/10.1002/bdra.20211

17.

Mossey

Little

Munger

Dixon

Shaw

. Cleft lip and palate. Lancet. 2009;374(9703):1773–1785. doi:10.1016/S0140-6736(09)60695-4

18.

NBDPN Guidelines for Conducting Birth Defects Surveillance. Chapter 8 Statistics, Calculating Birth Prevalence; 2019. Accessed July 17, 2019. https://www.nbdpn.org/docs/Ch_8_Statistics6-04_2016DEC14.pdf

19.

Nicholls

Harper

Robinson

Persson

Selvey

. Adult specific life outcomes of cleft lip and palate in a western Australian cohort. Cleft Palate Craniofac J. 2016;55(10):419–1429.

20.

Nyberg

Sickler

Hegge

Kramer

Kropp

. Fetal cleft lip with and without cleft palate: US classification and correlation with outcome. Radiology. 1995;195(3):677–684. doi:10.1148/radiology.195.3.7753993

21.

Pinquart

Shen

. Depressive symptoms in children and adolescents with chronic physical illness: an updated meta-analysis. J Pediatr Psychol. 2010;36(4):375–384. doi:10.1093/jpepsy/jsq104

22.

US Department of Health and Human Services, Public Health Service, Health Care Financing Administration. ICD-9-CM: International Classification of Diseases, 9th Revision, Clinical Modification (Based on the Official Version of the World Health Organization’s 9th Revision, International Classification of Diseases). Washington; 1980.

23.

WA Health. Western Australia’s Mothers and Babies: 2014. 32nd Annual Report of the WA Midwives’ Notification System. October 2018. Government of Western Australia Health Department. ISSN: 0816-2999. Table 79. (5) (PDF) Description of total population hospital admissions for cleft lip and/or palate in Australia. 1980. Accessed January 08, 2019. https://www.researchgate.net/publication/286400426_Description_of_total_population_hospital_admissions_for_cleft_lip_andor_palate_in_Australia

24.

Watkins

Meyer

Strauss

Aylsworth

. Classification, epidemiology, and genetics of orofacial clefts. Clin Plast Surg. 2014;41(2):149–163. doi:10.1016/j.cps.2013.12.003

25.

Wehby

Pedersen

Murray

Christensen

. The effects of oral clefts on hospital use throughout the lifespan. BMC Health Serv Res. 2012;12(1):58–74. doi:10.1186/1472-6963-12-58

26.

Weiss

Kotelchuck

Grosse

Manning

Anderka

Wyszynski

Howard

Wanda

Raul

Emily

, et al. Hospital use and associated costs of children aged zero-to-two years with craniofacial malformations in Massachusetts. Birth Defects Res A Clin Mol Teratol. 2009;85(11):925–934.

Supplementary Material

Please find the following supplemental material available below.

For Open Access articles published under a Creative Commons License, all supplemental material carries the same license as the article it is associated with.

For non-Open Access articles published, all supplemental material carries a non-exclusive license, and permission requests for re-use of supplemental material or any part of supplemental material shall be sent directly to the copyright owner as specified in the copyright notice associated with the article.

0.00 MB

0.01 MB