Structure And Function of Human Salivary Mucins

Nugent, J. and O'Connor, M., Eds., Mucus and mucosa, CIBA Symp., 1, 109, 1984.

Tabak, L.A., Levine, M.J., Mandel, I.D., and Ellison, S.A., Role of salivary mucins in the protection of the oral cavity, J. Oral. Pathol., 11, 1, 1982.

Mandel, I.D., The functions of saliva, J. Dent. Res., 66, 623, 1982.

Fox, P.C., Van Der Ven, P.F., Sonies, B.C., Weiffenbach, J.M., and Baum, B.J., Xerostomia: evaluation of a symptom with increasing significance, J. Am. Dent. Assoc., 110, 519, 1985.

Levine, M.J., Aguirre, A., Hatton, M.N., and Tabak, L.A., Artifical salivas: present and future, J. Dent. Res., 66, 693, 1987.

Edgerton, M., Tabak, L.A., and Levine, M.J., Saliva: a significant factor in removable prosthodontic treatment, J. Prosthet. Dent., 57, 57, 1987.

Tabak, L.A., Genetic control of salivary mucin formation, in Molecular Genetics of the Mouth: Frontiers of Oral Biology, Ferguson, D., Ed., S. Karger, New York, in press.

Quissell, D.O. and Tabak, L.A., Salivary mucin secretion, in Handbook of Physiology - The Gastrointestinal System III, Forte, J. G., Ed., American Physiological Society, Bethesda, 1989, 79.

Levine, M.J., Reddy, M.S., Tabak, L.A., Loomis, R.E., Bergey, E.J., Jones, P.C., Cohen, R.E., Stinson, M.W., and Al-Hashimi, I., Structural aspects of salivary glycoproteins, J. Dent. Res., 66, 436, 1987.

Levine, M.J., Jones, P.C., Loomis, R.E., Reddy, M.S., Al-Hashimi, I., Bergey, E.J., Bradway, S.D., Cohen, R.E., and Tabak, L.A., Functions of human saliva and salivary mucins: an overview, in Oral Mucosal Disease: Biology, Etiology, and Therapy, Proc. 2nd Dows Symp., Mackenzie, I. C., Squier, C. A., and Dabelsteen, E., Eds., Laegeforeningens Forlag, 1987, 24.

Cohen, R.E. and Levine, M.J., Salivary glycoproteins, in Human Saliva: Clinical Chemistry and Microbiology, Tenovuo, J. 0., Ed., CRC Press, Boca Raton, FL, 1989, chap. 4.

Clamp, J.R., Allen, A., Gibbons, R.A., and Roberts, G.P., Chemical aspects of mucus, Br. Med. Bull., 34, 25, 1978.

Masson, P.L., Carbohydrate component of cervical mucus, in Cervical Mucus in Human Reproduction, Epstein, A., Ed., Scripner, Copenhagen, 1972, 82.

Loomis, R.E., Prakobphol, A., Levine, M.J., Reddy, M.S., and Jones, P.C., Biochemical and biophysical comparison of two mucins from human submandibular-sublingual saliva, Arch. Biochem. Biophys., 258, 452, 1987.

Gottschalk, A., Bhargava, A.S., and Murty, V.L.N., Submaxillary gland glycoproteins, in Glycoproteins: Their Compositions, Structure, and Function, 2nd ed., Gottschalk, A., Ed., Elsevier, Amsterdam, 1972, 810.

Prakobphol, A., Levine, M.J., Tabak, L.A., and Reddy, M.S., Purification of a low-molecular-weight, mucin-type glycoprotein from human submandibular-sublingual saliva, Carbohydr. Res., 108, 111, 1982.

Reddy, M.S., Levine, M.J., and Prakobphol, A., Oligosaccharide structures of the low-molecular-weight salivary mucin from a normal individual and one with cystic fibrosis. J. Dent. Res., 64, 33, 1985.

Slomiany, B.L., Murty, V.L.N., Slomiany, A., Zielinski, J., and Mandel, I.D., Mucus glycoprotein of human saliva: differences in the associated and covalently bound lipids with caries, Biochem. Biophys. Acta, 882, 18, 1986.

Cohen, R.E., Aguirre, A., Jones, P.C., Reddy, M.S., Neiders, M.E., and Levine, M.J., Immunocytochemistry of human salivary mucins, J. Dent. Res., 66(Abstr. 302), 1987.

Edgerton, M., Cohen, R.E., Aguirre, A., Reddy, M.S., and Levine, M.J., Immunochemical analysis of human palatine salivary mucins, J. Dent. Res., 67 (Abstr. 828), 1988.

Roberton, A.M., Mantle, M., Fahim, R.E.F., Specian, R.D., Bennick, A., Kawagishi, S., Sherman, P., and Forstner, J.F., The putative "link" glycopeptide associated with mucus glycoproteins- composition and properties of preparations from the gastrointestinal tracts of several mammals, Biochem. J., 261, 637, 1989.

Hill, H.D., Jr., Reynolds, J.A., and Hill, R.L., Purification, composition, molecular weight, and subunit structure of ovine submaxillary mucin, J. Biol. Chem., 252, 3791, 1977.

Eckhardt, A.E., Timpte, C.S., Abernethy, J.L., Toumadje, A., Johnson, W.C., Jr., and Hill, R.L., Structural properties of porcine submaxillary gland apomucin, J. Biol. Chem., 262, 11339, 1987.

Timpte, C.S., Eckhardt, A.E., Abernethy, J.L., and Hill, R.L., Porcine submaxillary gland apomucin contains tandemly repeated identical sequences of 81 residues, J. Biol. Chem., 263, 1081, 1988.

Bennick, A., Structural and genetic aspects of proline-rich proteins, J. Dent. Res., 66, 457, 1987.

Ann, D.K., Clememts, S., Johnstone, E.M., and Carlson, D.M., Induction of tissue-specific proline rich protein multigene families in rat and mouse parotid glands by isoproterenol, J. Biol. Chem., 262, 899, 1987.

Garfinkle, M.D., Pruitt, R.E., and Meyerowitz, E.M., DNA sequences, gene regulation and modular protein evolution in the drosphila 68C Glue gene cluster, J. Mol. Biol., 168, 765, 1983.

Dickinson, D.P., Mirels, L., Tabak, L.A., and Gross, K.W., Rapid evolution of variants in a rodent multi-gene family encoding salivary proteins, Mol. Biol. E vol., 6, 80, 1989.

Heinrich, G. and Habener, J.F., Genes encoding proteins with homologous contiguous repeat sequences are highly expressed in the serous cells of the rat submandibular gland, J. Biol. Chem., 262, 5260, 1987.

Mirels, L., Bedi, G.S., Dickinson, D.P., Gross, K.W., and Tabak, L.A., Molecular characterization of glutamine/glutamic acid-rich secretory proteins from rat submandibular glands, J. Biol. Chem., 262, 7289, 1987.

Tabak, L.A., Levine, M.J., Jain, N.K., Bryan, A.R., Cohen, R.E., Monte, L.D., Zawacki, S., Nancollas, G.H., Slomiany, A., and Slomiany, B.L., Adsorption of human salivary mucin to hydroxyapatite, Arch. Oral. Biol., 30, 423, 1985.

Fisher, S.J., Prakbphol, A., Kajisa, L., and Murray, P.A., External radiolabelling of components of pellicle on human enamel and cementum, Arch. Oral Biol., 32, 509, 1987.

Al-Hashimi, I. and Levine, M.J., Characterization of in vitro salivary-derived enamel pellicle, Arch. Oral Biol., 34, 289, 1989.

Al-Hashimi, I., Dickinson, P.D., and Levine, M.J., Purification, molecular cloning, and sequencing of salivary cystatin SA-I, J. Biol. Chem., 263, 9381, 1988.

Tabak, L.A. and Bowen, W.H., Roles of saliva (pellicle), diet, and nutrition on plaque formation, J. Dent. Res., 68, 1560, 1989.

Amerongen, A.V.N., Oderkerk, C.H., and Driessen, A.A., Role of mucins from human whole saliva in the protection of tooth enamel against demineralization in vitro, Caries Res., 21, 297, 1987.

Bradway, S.D., Bergey, E.J., Jones, P.C., and Levine, M.J., Oral mucosal pellicle: adsorption and transpeptidation of salivary components to buccal epithelial cells, Biochem. J., 261, 887, 1989.

Slomiany, B.L., Murty, V.L.N., Mandel, I.D., Zalesna, G., and Slomiany, A., Physico-chemical characteristics of mucus glycoproteins and lipids of the human oral mucosal mucus coat in relation to caries susceptibility, Arch. Oral Biol., 34, 229, 1989.

Hatton, M.N., Loomis, R.E., Levine, M.J., and Tabak, L.A., Masticatory lubrication: role of carbohydrate in the lubricating property of a salivary glycoprotein-albumin complex, Biochem. J., 230, 817, 1985.

Hatton, M.N., Levine, M.J., Margarone, J.E., and Aguirre, A., Lubrication and viscosity features of human saliva and commercially available saliva substitutes, J. Oral Maxillofac. Surg., 45, 496, 1987.

Aguirre, A., Mendoza, B., Levine, M.J., Hatton, M.N., and Douglas, W.H., In vitro characterization of human salivary lubrication, Arch. Oral Biol., 34, 675, 1989.

Vissink, A., Waterman, H.A., 's-Gravenmade, E.J., Panders, A.K., and Vermey, A., Rheological properties of saliva substitutes containing mucin, carboxymethylcellulose or polyethylenoxide, J. Oral Pathol., 13, 22, 1984.

Vissink, A., De Jong, H.P., Busscher, H.J., Arends, J., and 's-Gravenmade, E.J., Wetting properties of human saliva and saliva substitutes, J. Dent. Res., 65, 1121, 1986.

Duxbury, A.J., Thakker, N.S., and Wastell, D.G., A double-blind cross-over trial of a mucin-containing artificial saliva, Br. Dent. J., 166, 115, 1989.

Gans, R.F., Watson, G.E., and Tabak, L.A., A new assessment of salivary lubrication, Arch. Oral Biol. 35, 487, 1990.

Dawes, C., A mathematical model of salivary clearance of sugar from the oral cavity, Caries Res., 17, 321, 1983.

Dawes, C., Watanabe, S., Biglow-Lecomte, P., and Dibdin, G.H., Estimation of the velocity of the salivary film at some different locations in the mouth, J. Dent. Res., 68, 1479, 1989.

Milne, R.W. and Dawes, C., The relative contributions of different salivary glands to the blood group activity of whole saliva in humans, Vox Sang., 25, 298, 1973.

Creeth, J.M., Bridge, J.L.N., and Horton, J.R., An interaction between lysozyme and mucous glycoproteins, Biochem. J., 181, 717, 1979.

Stinson, M.W., Levine, M.J., Cavese, J.M., Prakobphol, A., Murray, P.A., Tabak, L.A., and Reddy, M.S., Adherence of Streptococcus sanguis to salivary mucin bound to glass, J. Dent. Res., 61, 1390, 1982.

Levine, M.J., Herzberg, M.C., Levine, M.S., Ellison, S.A., Stinson, M.W., Li, H.C., and Van Dyke, T., Specificity of salivary-bacterial interactions: role of terminal sialic acid residues in the interaction of salivary glycoproteins with Streptococcus sanguis and Streptococcus mutans, Infect. Immun., 19, 107, 1978.

Murray, P.A., Levine, M.J., Tabak, L.A., and Reddy, M.S., Specificity of salivary-bacterial interactions. I. Evidence for a lectin on Streptococcus sanguis with specificity for a NeuAca2, 3Galβ1, 3GalNAc sequence, Biochem. Biophys. Res. Commun., 106, 390, 1982.

Hoskins, L.C. and Boulding, E.T., Degradation of blood group antigens in human colon ecosystems. I. In vitro production of ABH blood group-degrading enzymes by enteric bacteria, J. Clin. Invest., 57, 63, 1976a.

Hoskins, L.C. and Boulding, E.T., Degradation of blood group antigens in human colon ecosystems. II. A gene interaction in man that affects the fecal population density of certain enteric bacteria, J. Clin. Invest., 57, 74, 1976.