An important step in preventing methotrexate (MTX) toxicity is to assess patient self-medication of over-the-counter drugs before high-dose methotrexate (HDMTX) treatment is administered. Nonsteroidal anti-inflammatory drugs given within a 10-day period before a patient receives HDMTX leads to a decreased MTX excretion rate causing MTX toxicity. Education of the nursing staff and patients and their families is vital to avoid the potentially dangerous effects of a delayed MTX excretion rate.
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References
1.
Laws of NewJersey, 1948; Chapter 87. Trenton, New Jersey: MacCrellish & Quigley Co., 1948.
2.
Pearson, A."Education in the New Halloway Prison for Women."Adult Education (Eng.)44 (1971), 33-36.
3.
Perrow, Charles."Demystifying Organizations."Paper presented at Rutgers University, Graduate School of Education Conference: "Can We Renew Our Educational Organizations?" March 10, 1978.
4.
State of New Jersey: Assembly, No. 86. "An Act concerning State aid for the education of children in State Facilities..." Introduced by Assemblyman Newman; adopted June 12, 1978.
5.
Barra, J.A."Selected Cultural Variables and the Reading Achievement of Black Inner-City School Children of Washington, D. C." Unpublished Doctoral Dissertation, Catholic University of America, 1973.
6.
Bruininks, R.H."Auditory and Visual Perceptual Skills Related to the Reading Performance of Disadvantaged Boys."Perceptual and Motor Skills29 (1969), 179-186.
7.
Busch, J.C., and DeRidder, L.M."Note on Control For Intelligence Studies of Field Dependence with Young Children."Perceptual and Motor Skills32 (1971), 337-338.
8.
Carbuhn, W.M."Predicting GED Test Performance of Urban Job Corpsmen."Educational and Psychological Measurement30 (1970), 443-448.
9.
Case, R."Social Class Differences in Intellectual Development: A Neo-Piagetian Investigation."Canadian Journal of Behavioural Science7 (1975), 244-261.
10.
Dreyer, Albert S., et al."Portable Rod and Frame Tests as a Measure of Cognitive Style in Kindergarten Children."Perceptual and Motor Skills33 ( 1971), 775-781.
11.
Dubois, T.E., and Cohen, Walter."Relationship Between Measures of Psychological Differentiation and Intellectual Ability." j 3 (1970), 411-416.
12.
Fischer, J.K."A Comparison of High School Senior and Candidate Performance on the Tests of General Educational Development." Unpublished Doctoral Dissertation, State University of Rutgers, 1977.
