Symptom management in pediatric oncology remains a problem. Despite remarkable pharmacologic and surgical advances, children continue to report symptoms as the most troublesome aspect of cancer treatment. However, there are additional therapies that are not considered standard symptom management, such as acupuncture and guided imagery. These nonpharmacologic adjunctive therapies are a potential source of assistance for children with unrelenting pain, nausea, or other unpleasant symptoms due to cancer treatment. This article summarizes research studies that have examined nonpharmaco-logic therapies for symptom management in pediatric oncology.
Antonarakis, E. S., Evans, J. L., Heard, G. F., Noonan, L. M., Pizer, B. L., & Hain, R. D. (2004). Prophylaxis of acute chemotherapy-induced nausea and vomiting in children with cancer: What is the evidence? Pediatric Blood and Cancer, 43(6), 651-658.
2.
Barrera, M. E., Rykov, M. H., & Doyle, S. L. (2002). The effects of interactive music therapy on hospitalized children with cancer: A pilot study. Psychooncology, 11(5), 379-388.
3.
Blount, R. L., Powers, S. W., Cotter, M. W., Swan, S., & Free, K. (1994). Making the system work: Training pediatric oncology patients to cope and their parents to coach them during BMA/LP procedures. Behavior Modification, 18(1), 6-31.
4.
Broome, M. E., Lillis, P. P., McGahee, T. W., & Bates, T. (1992). The use of distraction and imagery with children during painful procedures. Oncology Nursing Forum, 19(3), 499-502.
5.
Cotanch, P., Hockenberry, M., & Herman, S. (1985). Self-hypnosis as antiemetic therapy in children receiving chemotherapy. Oncology Nursing Forum, 12(4), 41-46.
6.
Dahlquist, L. M., Busby, S. M., Slifer, K. J., Tucker, C. L., Eischen, S., Hilley, L., et al. (2002). Distraction for children of different ages who undergo repeated needle sticks. Journal of Pediatric Oncology Nursing, 19(1), 22-34.
7.
Dahlquist, L. M., Gil, K. M., Armstrong, F. D., Ginsberg, A., & Jones, B. (1985). Behavioral management of children’s distress during chemotherapy. Journal of Behavior Therapy and Experimental Psychiatry, 16(4), 325-329.
8.
Dahlquist, L. M., Pendley, J. S., Landthrip, D. S., Jones, C. L., & Steuber, C. P. (2002). Distraction intervention for preschoolers undergoing intramuscular injections and subcutaneous port access. Health Psychology, 21(1), 94-99.
9.
Enskar, K., Carlsson, M., Hamrin, E., & Kreuger, A. (1996). Swedish health care personnel’s perceptions of disease and treatment-related problems experienced by children with cancer and their families. Journal of Pediatric Oncology Nursing, 13(2), 61-70; discussion 71.
10.
Favara-Scacco, C., Smirne, G., Schiliro, G., & Di Cataldo, A. (2001). Art therapy as support for children with leukemia during painful procedures. Medical and Pediatric Oncology, 36(4), 474-480.
11.
Frankenfield, P. K. (1996). The power of humor and play as nursing interventions for a child with cancer: A case report. Journal of Pediatric Oncology Nursing, 13(1), 15-20.
12.
Gershon, J., Zimand, E., Lemos, R., Rothbaum, B. O., & Hodges, L. (2003). Use of virtual reality as a distractor for painful pro cedures in a patient with pediatric cancer: A case study. Cyberpsychology and Behavior, 6(6), 657-661.
13.
Gershon, J., Zimand, E., Pickering, M., Rothbaum, B. O., & Hodges, L. (2004). A pilot and feasibility study of virtual reality as a distraction for children with cancer. Journal of the American Academy of Child and Adolescent Psychiatry, 43(10), 1243-1249.
14.
Giordano, J., Engebretson, J., & Garcia, M. K. (2005). Challenges to complementary and alternative medical research: Focal issues influencing integration into a cancer care model. Integrative Cancer Therapies, 4(3), 210-218.
15.
Hawkins, P. J., Liossi, C., Ewart, B. W., Hatira, P., & Kosmidis, V. H. (1998). Hypnosis in the alleviation of procedure related pain and distress in paediatric oncology patients. Contemporary Hypnosis, 15, 199-207.
16.
Hilgard, J. R., & LeBaron, S. (1982). Relief of anxiety and pain in children and adolescents with cancer: Quantitative measures and clinical observations. International Journal of Clinical and Experimental Hypnosis, 30(4), 417-442.
17.
Jacknow, D. S., Tschann, J. M., Link, M. P., & Boyce, W. T. (1994). Hypnosis in the prevention of chemotherapy-related nausea and vomiting in children: A prospective study. Journal of Developmental and Behavioral Pediatrics, 15(4), 258-264.
18.
Jay, S., Elliott, C. H., Fitzgibbons, I., Woody, P., & Siegel, S. (1995). A comparative study of cognitive behavior therapy versus general anesthesia for painful medical procedures in children. Pain, 62(1), 3-9.
19.
Jemal, A., Murray, T., Ward, E., Samuels, A., Tiwari, R. C., Ghafoor, A., et al. (2005). Cancer statistics, 2005. CA: A Cancer Journal for Clinicians, 55(1), 10-30.
20.
Katz, E. R., Kellerman, J., & Ellenberg, L. (1987). Hypnosis in the reduction of acute pain and distress in children with cancer. Journal of Pediatric Psychology, 12(3), 379-394.
21.
Kaufman, K. L., Tarnowski, K. J., & Olson, R. (1989). Self-regulation treatment to reduce the aversiveness of cancer chemotherapy. Journal of Adolescent Health Care, 10(4), 323-327.
22.
Kazak, A. E., Penati, B., Boyer, B. A., Himelstein, B., Brophy, P., Waibel, M. K., et al. (1996). A randomized controlled prospective outcome study of a psychological and pharmacological intervention protocol for procedural distress in pediatric leukemia. Journal of Pediatric Psychology, 21(5), 615-631.
23.
Kellerman, J., Zeltzer, L., Ellenberg, L., & Dash, J. (1983). Adolescents with cancer: Hypnosis for the reduction of the acute pain and anxiety associated with medical procedures. Journal of Adolescent Health Care, 4(2), 85-90.
24.
Klosky, J. L., Tyc, V. L., Srivastava, D. K., Tong, X., Kronenberg, M., Booker, Z. J., et al. (2004). Brief report: Evaluation of an interactive intervention designed to reduce pediatric distress during radiation therapy procedures. Journal of Pediatric Psychology, 29(8), 621-626.
25.
Kuttner, L., Bowman, M., & Teasdale, M. (1988). Psychological treatment of distress, pain, and anxiety for young children with cancer. Journal of Developmental and Behavioral Pediatrics, 9(6), 374-381.
26.
LaBaw, W., Holton, C., Tewell, K., & Eccles, D. (1975). The use of self-hypnosis by children with cancer. American Journal of Clinical Hypnosis, 17(4), 233-238.
27.
Liossi, C., & Hatira, P. (1999). Clinical hypnosis versus cognitive behavioral training for pain management with pediatric cancer patients undergoing bone marrow aspirations. International Journal of Clinical and Experimental Hypnosis, 47(2), 104-116.
28.
Liossi, C., & Hatira, P. (2003). Clinical hypnosis in the alleviation of procedure-related pain in pediatric oncology patients. International Journal of Clinical and Experimental Hypnosis, 51(1), 4-28.
29.
Manne, S. L., Redd, W. H., Jacobsen, P. B., Gorfinkle, K., Schorr, O., & Rapkin, B. (1990). Behavioral intervention to reduce child and parent distress during venipuncture. Journal of Consulting and Clinical Psychology, 58(5), 565-572.
30.
Mason, S., Johnson, M. H., & Woolley, C. (1999). A comparison of distractors for controlling distress in young children during medical procedures. Journal of Clinical Psychology in Medical Settings, 6(3), 239-248.
31.
Moore, J. B., & Beckwitt, A. E. (2004). Children with cancer and their parents: Self-care and dependent-care practices. Issues in Comprehensive Pediatric Nursing, 27(1), 1-17.
32.
National Center for Complementary and Alternative Medicine (NCCAM). (2006). Cancer and complementary and alternative medicine. Retrieved September 5, 2006, from http://nccam.nih.gov/health/camcancer/
33.
Olness, K. (1981). Imagery (self-hypnosis) as adjunct therapy in childhood cancer: Clinical experience with 25 patients. American Journal of Pediatric Hematology/Oncology, 3(3), 313-321.
34.
Pederson, C. (1996). Promoting parental use of nonpharmaco-logic techniques with children during lumbar punctures. Journal of Pediatric Oncology Nursing, 13(1), 21-30.
35.
Pfaff, V. K., Smith, K. E., & Gowan, D. (1989). The effects of music-assisted relaxation on the distress of pediatric cancer patients undergoing bone marrow aspirations. Children’s Health Care, 18(4), 232-236.
36.
Post-White, J., Hawks, R., O’Mara, A., & Ott, M. J. (2006). Future directions of CAM research in pediatric oncology. Journal of Pediatric Oncology Nursing, 23(5), 265-268.
37.
Redd, W. H., Jacobsen, P. B., Die-Trill, M., Dermatis, H., McEvoy, M., & Holland, J. C. (1987). Cognitive/attentional distraction in the control of conditioned nausea in pediatric cancer patients receiving chemotherapy. Journal of Consulting and Clinical Psychology, 55(3), 391-395.
38.
Reeb, R. N., & Bush, J. P. (1996). Preprocedural psychological preparation in pediatric oncology: A process-oriented intervention study. Children’s Health Care, 25(4), 265-279.
39.
Reindl, T. K., Geilen, W., Hartmann, R., Wiebelitz, K. R., Kan, G., Wilhelm, I., et al. (2005). Acupuncture against chemotherapy-induced nausea and vomiting in pediatric oncology Interim results of a multicenter crossover study. Supportive Care in Cancer, 14(2), 172-176.
40.
Robb, S. L., & Ebberts, A. G. (2003). Songwriting and digital video production interventions for pediatric patients undergoing bone marrow transplantation, part I: An analysis of depression and anxiety levels according to phase of treatment. Journal of Pediatric Oncology Nursing, 20(1), 2-15.
41.
Tsao, J. C., & Zeltzer, L. K. (2005). Complementary and alternative medicine approaches for pediatric pain: A review of the state-of-the-science. Evidence-Based Complementary and Alternative Medicine, 2(2), 149-159.
42.
Tyc, V. L., Leigh, L., Mulhern, R. K., Srivastava, D. K., & Bruce, D. (1997). Evaluation of a cognitive-behavioral intervention for reducing distress in pediatric cancer patients undergoing magnetic resonance imaging procedures. International Journal of Rehabilitation & Health, 3(4), 267-279.
43.
Vannorsdall, T., Dahlquist, L., Pendley, J. S., & Power, T. (2004). The relation between nonessential touch and children's distress during lumbar punctures. Children's Health Care, 33(4), 299-315.
44.
Wall, V. J., & Womack, W. (1989). Hypnotic versus active cognitive strategies for alleviation of procedural distress in pediatric oncology patients. American Journal of Clinical Hypnosis, 31(3), 181-191.
45.
Weekes, D. P., Kagan, S. H., James, K., & Seboni, N. (1993). The phenomenon of hand holding as a coping strategy in adolescents experiencing treatment-related pain. Journal of Pediatric Oncology Nursing, 10(1), 19-25.
46.
Zeltzer, L., Dolgin, M. J., LeBaron, S., & LeBaron, C. (1991). A randomized, controlled study of behavioral intervention for chemotherapy distress in children with cancer. Pediatrics, 88(1), 34-42.
47.
Zeltzer, L., Kellerman, J., Ellenberg, L., & Dash, J. (1983). Hypnosis for reduction of vomiting associated with chemotherapy and disease in adolescents with cancer. Journal of Adolescent Health Care, 4(2), 77-84.
48.
Zeltzer, L., & LeBaron, S. (1982). Hypnosis and nonhypnotic techniques for reduction of pain and anxiety during painful procedures in children and adolescents with cancer. Journal of Pediatrics, 101(6), 1032-1035.
49.
Zeltzer, L., LeBaron, S., & Zeltzer, P. M. (1984). The effectiveness of behavioral intervention for reduction of nausea and vomiting in children and adolescents receiving chemotherapy. Journal of Clinical Oncology, 2(6), 683-690.
