A 16-year-old female Vietnamese pot-bellied pig was euthanized after a period of inappetence and weight loss. Diffuse cystic endometrial hyperplasia and endometrial adenocarcinoma with metastasis to lymph nodes, liver, and lung were diagnosed. This report follows the recent description of cystic endometrial hyperplasia and uterine leiomyomas in 3 aged female Vietnamese pot-bellied pigs. The findings in this report and previous reports suggest that pigs may develop some similar age-related uterine lesions as do women.
References
1.
AkkermansJPvan BeusekomWJ: 1984, Tumors and tumor-like lesions in the genitalia of sows. Vet Q6:90–96.
2.
AndersonLJSandisonATJarrettWF: 1969, A British abattoir survey of tumours in cattle, sheep and pigs. Vet Rec84:547–551.
3.
BrintonLABermanMLMortelR: 1992, Reproductive, menstrual, and medical risk factors for endometrial cancer: results from a case-control study. Am J Obstet Gynecol167:1317–1325.
4.
BrodeyRSRoszelJF: 1967, Neoplasms of the canine uterus, vagina, and vulva: a clinicopathologic survey of 90 cases. J Am Vet Med Assoc151:1294–1307.
5.
ChangKKurtzHJMirochaCJ: 1979, Effects of the mycotoxin zearalenone on swine reproduction. Am J Vet Res40:1260–1267.
6.
CrumPC: 1999, The female genital tract. In: Pathologic basis of disease, ed. CotranRSKumarVCollinsT, pp. 1035–1091. W. B. Saunders, Philadelphia, PA.
7.
FoxH: 1912, Observations upon neoplasms in wild animals in the Philadelphia zoological gardens. J Pathol Bacteriol12:217–231.
8.
Garcia-InglesiasMJBravo-MoralAMPerez-MartinezC: 1995, Incidence and pathomorphology of uterine tumors in the cow. Zentbl Vetmed Reihe A42:421–429.
9.
KennedyPCMillerRB: 1993, The female genital system. In: Pathology of domestic animals, ed. JubbKVFKennedyPCPalmerN, 4th ed., pp. 349–370. Academic Press, San Diego, CA.
10.
KimminsSMacLarenLA: 2001, Oestrous cycle and pregnancy effects on the distribution of oestrogen and progesterone receptors in bovine endometrium. Placenta22:742–748.
11.
KurmanRJKaminskiPFNorrisHJ: 1985, The behavior of endometrial hyperplasia. A long-term study of “untreated” hyperplasia in 170 patients. Cancer56:403–412.
12.
LoebL: 1900, Tumor of the uterus of a sow (adenocarcinoma). Trans Chicago Pathol Soc4:287–288.
13.
MundayJSStedmanNL: 2002, Uterine leiomyomas in two Vietnamese pot-bellied pigs (Sus scrofa). Vet Pathol39:580–583.
14.
RonnettBMKurmanRJ: 2002, Precursor lesions of endometrial carcinoma. In: Baustein's pathology of the female genital tract, ed. KurmanRJ, 5th ed., pp. 467–500. Springer-Verlag, New York, NY.
15.
WeisbrothSH: 1994, Neoplastic diseases. In: The biology of the laboratory rabbit, ed. ManningPJRinglerDH, 2nd ed., pp. 259–292. Academic Press, New York, NY.
16.
WerdinRWoldK: 1976, Uterine carcinoma in a sow. Vet Pathol13:451–452.
