A 7-year-old intact female red-eared slider (Trachemys scripta elegans) presented with anorexia of 2–3-weeks duration. Coelomic radiographs demonstrated 3 shelled eggs in the right cavity. Hormone therapy failed to induce oviposition. Exploratory laparotomy revealed 3 calcified eggs in the right oviduct and a large mass obliterating the left ovary. The large, multilobulate mass had scattered, firm, white nodules and weighed 450 g. Histopathology revealed a malignant teratoma composed of immature embryonal and extraembryonal elements derived from all 3 germ layers with multifocal epithelial anaplasia. This is the first report of a teratoma in chelonian gonadal tissue. Teratomas and reptilian gonadal neoplasia are reviewed.
References
1.
AndersonNLWilliamsJSagartzJE: 1996, Ovarian teratoma in a green iguana (iguana iguana). J Zoo Wildl Med27:90–95
2.
AndersonWIJohnsonRC: 1988, Testicular teratoma and seminoma in a woodchuck. Vet Pathol25:400
3.
BasarabaRJKraftSLAndrewsGA: 1998, An ovarian teratoma in a cat. Vet Pathol35:141–144
4.
BaskinGBSoikeKJorgeSKWolfRW: 1982, Ovarian teratoma in an African green monkey (Cercopithecus aethiops). Vet Pathol19:219–221
5.
BennettRA: 1989, Reptilian surgery. Part II. Management of surgical diseases. Compend Cont Ed Pract Vet11:122–133
6.
CullenJMNewboldJEShermanGJ: 1991, A teratoma in a duck infected congenitally with duck hepatitis B virus. Avian Dis35:638–641
7.
DehnerLPNorrisHJGarnerFMTaylorHB: 1970, Comparative pathology of ovarian neoplasms. 3. Germ cell tumors of canine, bovine, feline, rodent and human species. J Comp Pathol80:299–306
8.
FrazerGSRobertsonJTBoyceRW: 1988, Teratocarcinoma of the ovary in a mare. J Am Vet Med Assoc193:953–955
9.
FriskCSWagnerJEDoyleRE: 1978, An ovarian teratoma in a guinea pig. Lab Anim Sci28(2):199–201
10.
GelbergHBMcEnteeK: 1985, Feline ovarian neoplasms. Vet Pathol22:572–576
11.
GreenleePGPatnaikAK: 1985, Canine ovarian tumors of germ cell origin. Vet Pathol22(2):117–122
12.
HelmboldtCFMigakiGLangheinrichKAJakowskiRM: 1974, Teratoma in domestic fowl (Gallus gallus). Avian Dis18:142–148
13.
HomerBLRiggMW: 1991, Cranial teratomas in two domestic ducks (Anas platyrhynchos domesticus). Avian Dis35:994–998
14.
KennedyPCMillerRB: 1993, Female genital system. In: Pathology of domestic animals, ed. JubbKVFKennedyPCPalmerN, 4th ed., pp. 364369. Academic Press, New York, NY
15.
KleinMK: 1989, Tumors of the female reproductive system. In: Small animal clinical oncology, ed. WithrowSJMacEwenEG, 2nd ed., pp. 347355. WB Saunders, Philadelphia, PA
16.
LinderDMcCawBKHechtF: 1975, Parthenogenic origin of benign ovarian teratomas. N Engl J Med292:63–66
17.
MachotkaSVWisserJIppenRNawabE: 1992, Report of dysgerminoma in the ovaries of a snapping turtle (Chelydra serpentina) with discussion of ovarian neoplasms reported in reptilians and women. In Vivo6(4):349–354
18.
NagashimaYHoshiKTanakaR: 2000, Ovarian and retroperitoneal teratomas in a dog. J Vet Med Sci62(7):793–795
19.
NielsenSWKennedyPC: 1990, Tumors of the genital systems. In: Tumors in domestic animals, ed. MoultonJE, 3rd ed., pp. 489491. University of California Press, Los Angeles, CA
20.
PatnaikAKGreenleePG: 1987, Canine ovarian neoplasms: A clinicopathologic study of 71 cases including histology of 12 granulosa cell tumors. Vet Pathol24:509–514
21.
PatnaikAKNafeLA: 1980, Intracranial teratocarcinoma in a dog. Vet Pathol17:764–769
22.
PatnaikAKSchaerMParksJLiuSK: 1976, Metastasizing ovarian teratocarcinoma in dogs. A report of two cases and review of literature. J Small Anim Pract17:235–246
23.
Schmid-BrazATCavalliLRCornelioDA: 2002, Comprehensive cytogenetic evaluation of a mature ovarian teratoma case. Cancer Genet Cytogenet132:165–168
24.
StolkA: 1958, Teratoma in a lizard, Proc K Ned Akad Wet61:192
25.
StolkA: 1958, Development of ovarian teratomas in viviparous toothcarps by pathological parthenogenesis. Nature183:763
TrastiSLSchlaferDH: 1999, Theriogenology question of the month. Malignant teratoma of the ovary. J Am Vet Med Assoc214:785–786
28.
WagnerHBarettonGBSchneiderbangerK: 1997, Sex chromosome determination in extragonadal teratomas by inter-phase cytogenetics: Clues to histiogenesis. Pediatr Pathol Lab Med17:401–412
