Substance abuse is a common presentation to Emergency Departments (ED). A case of gamma-hydroxybutyrate (GHB) presented to our ED is reported, its clinical history and findings, biochemical and toxicity is discussed. This drug affects the neurological, muscular, biochemical and sexual function.
GallimbertiL., CantonG., GentileN.Gamma hydroxybutyric acid for treatment of alcohol withdrawal syndrome.Lancet1989; 2(8666): 787–9.
2.
ChinM.Y., KrentzerR.A., DyerJ.E.Acute poisoning from gamma hydroxybutyrate in California.West J Med1992; 156(4): 380–4.
3.
HodgesB., EverettJ.Acute toxicity from homebrewed gamma hydroxybutyrate.J Am Board Fam Pract1998; 11(2): 154–7.
4.
MorgenthalerJohn and JoyDanGamma-hydroxybutyrate.Smart drug news. September 10th, 1994 [v3n6].
5.
TakaharaJ., YunokiS., YakushijiW.Stimulatory effects of gamma-hydroxybutyric acid on growth hormone and prolactin release in humans.J Clin Endocrinol Metab1977; 44(5): 1014–7.
LaboritH.Correlations between protein and serotonin synthesis during various activities of the central nervous system.Res Commun Chem Pathol Pharmacol1972; 3(1): 51–81.
BaseltR.C., CraveyR.H.Disposition of Toxic drugs and Chemicals in Man, 4th ed.Foster City, CA, CTI, 1995.
13.
EjjenhornM.J., SchonwaldS., OrdogG.Drug of Abuse. In EjjenhornM.J. (ed): Ejjenhorn's Medical Toxicology: Diagnosis and Treatment of Human Poisoning, 2nd ed.Baltimore, Williams and Wilkins, 1997.