A Serological Study of the Immune Status to Rubella in a Community in Singapore

Abstract

In 1986, a seroepidemiological study on rubella antibody was conducted in a public housing community in Singapore using the direct latex agglutination method. The overall seropositive rate was 78.1% (95% confidence limit: 73.5% to 82.7%). There was no significant association between age and immune status for both sexes. However, the seropositive rates for females aged 15 to 19 years and 20 to 24 years were significantly higher than for females in other age groups, reflecting the impact of the rubella immunisation programme launched in 1976. There is still a considerable number of susceptible females in the reproductive age group. An extension of the present programme to cover all persons above 12 months of age is recommended, as this would reduce the overall incidence of rubella, and hence congenital rubella, by conferring immunity to young children who presently act as reservoirs of infections.