Rare Case of Loperamide Toxicity in Neonates in Rural Backward North India

Abstract

The essence of the treatment of gastroenteritis in infancy and childhood is rehydration and the correction of electrolyte disturbances. Antidiarrheal agents are frequently used as an adjunct to treatment. Such drugs may not be as innocuous as previously thought to be, and there have been several reports of opiate like toxic effects with their usage in childhood diarrhea. In this case series, three cases of loperamide toxicity are reported.