Neonatal Calcinosis Cutis

Abstract

Background

Calcinosis cutis involves the deposition of calcium salt in the subcutaneous tissues and skin. This is commonly linked to connective tissue disorders or damaged tissues with normal or abnormal calcium/phosphorus metabolism. Iatrogenic cases are also there though rare.

Case Descriptions

Two male neonates born late preterm presented at 20 days (Case 1) and four weeks (Case 2), with firm linear erythematous swellings over extremities. Both neonates had a neonatal intensive care unit (NICU) stay after the birth for prematurity-related issues. Both were administered intravenous calcium during their NICU stay. There were no swellings at the time of discharge in both neonates.

Radiologically, both cases had calcification around the tibia and fibula (Case 1) and deposits in the right upper limb (Case 2). Both cases had normal calcium profiles and a negative sepsis workup. Both neonates improved clinically and radiologically on conservative management.

Management and Follow-up

Both cases were managed conservatively. Follow-up after three months showed complete resolution in Case 1 and partial resolution in Case 2. Regular monitoring is crucial for assessing progress.

Conclusion

Iatrogenic calcinosis cutis can arise from intravenous calcium administration and is generally self-limiting. Healthcare providers must be aware and careful in following up to manage and monitor this condition effectively.