Abstract
Aim
To assess the value of perfusion index (PI) and arrive at the ideal cut-off value of delta PI (DPI) (pre and postductal difference in PI) in identifying hemodynamically significant patent ductus arteriosus (HsPDA).
Methods
Prospective observational study was conducted on 156 preterm newborns of <37 weeks in the NICU of tertiary care center, from August 2019 to March 2020 after ethical clearance. 156 preterm babies were classified into noPDA, HsPDA and Non-HsPDA based on echocardiogram findings and compared with DPI value on Day 1 to 3 of life. Receiver operating characteristic (ROC) curve was constructed to establish cut-offs for DPI in diagnosing HsPDA. A P value <.05 is considered for statistical significance.
Results
There was a significantly lower PI in both preductal and post ductal limbs with HsPDA compared to other groups. A DPI Cut-off of 0.75 on day 2 of life has a sensitivity of 75%, specificity of 100% and positive predictive value (PPV) of 100% and a negative predictive value of 89%.
Conclusion
PI is a simple non-invasive bedside index predict the presence of a HsPDA in preterm newborns and DPI of >0.75 indicates for presence of HsPDA.
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