Isolated thrombocytopenia is a common finding in neonates and infants. Physicians should rule out infection at first. Meanwhile, neonatal lupus erythematosus is classically revealed by cutaneous and cardiac manifestations. Hematological involvement is possible but rare. In this article, we report the case of a one-month-old boy who had been suffering from isolated thrombocytopenia and was diagnosed with neonatal lupus.
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