Historical studies on the place of science in the development of nations and in the relation ships between the more wealthy powers and dependent countries have succeeded in broad ening the field of history of science to embrace situations and problems not previously appreciated. Such investigations help broaden the notion of science in keeping with what is really experienced in practice by taking several factors into account: the actors in science and technology, the content of knowledge, the context, and the social and cultural im plications. If the 'different' research approaches are confronted (involving studies of spa tially and temporally well-defined subjects according to discipline, etc.), they provide essen tial elements for comparative analysis which can trace the structural features of the diffusion, conjunction and integration of different sciences. These elements allow us to identify some significant epistemological problems posed by this rich chapter in the history of science.
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