RETRACTED: Circular RNA hsa_Circ_101141 as a Competing Endogenous RNA Facilitates Tumorigenesis of Hepatocellular Carcinoma by Regulating miR-1297/ROCK1 Pathway

Abstract

Keywords

circular RNA circ_101141 hepatocellular carcinoma miR-1297 ROCK1

At the request of the Journal Editor and Publisher, the following articles have been retracted

Zhang T, Zhang L, Han D, Tursun K, Lu X. Circular RNA hsa_Circ_101141 as a competing endogenous RNA facilitates tumorigenesis of hepatocellular carcinoma by regulating miR-1297/ROCK1 pathway. Cell Transplantation. 2020;29. doi:10.1177/0963689720948016.

Du C, Wang Y, Zhang Y, Zhang J, Zhang L, Li J. LncRNA DLX6-AS1 contributes to epithelial–mesenchymal transition and cisplatin resistance in triple-negative breast cancer via modulating miR-199b-5p/paxillin axis. Cell Transplantation. 2020;29. doi:10.1177/0963689720929983.

Wan Q, Chen Q, Cai D, Zhao Y, Wu X. OTUB2 promotes homologous recombination repair through stimulating Rad51 expression in endometrial cancer. Cell Transplantation. 2020;29. doi:10.1177/0963689720931433.

Li W, Yang X, Shi C, Zhou Z. Hsa_circ_002178 promotes the growth and migration of breast cancer cells and maintains cancer stem-like cell properties through regulating miR-1258/KDM7A axis. Cell Transplantation. 2020;29:. doi:10.1177/0963689720960174.

Liu G, Guo W, Rao M, Qin J, Hu F, Li K. circRNA hsa_circ_104566 sponged miR-338-3p to promote hepatocellular carcinoma progression. Cell Transplantation. 2020;29. doi:10.1177/0963689720963948.

Li J, Yu Z, Zhu Q, Tao C, Xu Q. hsa_circ_102559 acts as the sponge of miR-130a-5p to promote hepatocellular carcinoma progression through regulation of ANXA2. Cell Transplantation. 2020;29. doi:10.1177/0963689720968748.

Li J, Yang Y, Xu D, Cao L. hsa_circ_0023409 accelerates gastric cancer cell growth and metastasis through regulating the IRS4/PI3K/AKT pathway. Cell Transplantation. 2021;30. doi:10.1177/0963689720975390.

Wang Y, Yin L. LINC00461 promoted endometrial carcinoma growth and migration by targeting MicroRNA-219-5p/cyclooxygenase-2 signaling axis. Cell Transplantation. 2021;30. doi:10.1177/0963689721989616.

Wu J, Wang X, Yuan X, et al. Kinesin family member C1 increases temozolomide resistance of glioblastoma through promoting DNA damage repair. Cell Transplantation. 2021;30. doi:10.1177/0963689721991466.

Hui Y, Yang Y, Li D, et al. LncRNA FEZF1-AS1 modulates cancer stem cell properties of human gastric cancer through miR-363-3p/HMGA2. Cell Transplantation. 2020;29. doi:10.1177/0963689720925059.

After an internal investigation, Sage has become aware that the submissions contain indicators of third-party involvement. Due to concerns around author contributions to the articles, as well as concerns around the integrity of the research process, Sage and the Journal Editor retract the articles.

The authors have been informed of this decision using the email addresses provided at submission.

References

Wallace

Preen

Jeffrey

Adams

. The evolving epidemiology of hepatocellular carcinoma: a global perspective. Expert Rev Gastroenterol Hepatol. 2015;9(6):765–779.

Bosch

Ribes

Diaz

Cleries

. Primary liver cancer: worldwide incidence and trends. Gastroenterology. 2004;127(5 Suppl 1): S5–S16.

Ziogas

Tsoulfas

. Advances and challenges in laparoscopic surgery in the management of hepatocellular carcinoma. World J Gastrointest Surg. 2017;9(12):233–245.

Axley

Ahmed

Ravi

Singal

. Hepatitis C Virus and Hepatocellular Carcinoma: a narrative review. J Clin Transl Hepatol. 2018;6(1):79–84.

Petruzziello

. Epidemiology of hepatitis b virus (HBV) and hepatitis c virus (HCV) related hepatocellular carcinoma. Open Virol J. 2018;12:26–32.

Calderaro

Couchy

Imbeaud

Amaddeo

Letouze

Blanc

Laurent

Hajji

Azoulay

Bioulac-Sage

Nault

, et al Histological subtypes of hepatocellular carcinoma are related to gene mutations and molecular tumour classification. J Hepatol. 2017;67(4):727–738.

Homayounfar

Schwarz

Enders

Cameron

Baumhoer

Ramadori

Lorf

Gunawan

Sander

. Etiologic influence on chromosomal aberrations in European hepatocellular carcinoma identified by CGH. Pathol Res Pract. 2013;209(6):380–387.

Vilchez

Turcios

Marti

Gedaly

. Targeting Wnt/beta-catenin pathway in hepatocellular carcinoma treatment. World J Gastroenterol. 2016;22(2):823–832.

Haque

Harries

. Circular RNAs (circRNAs) in health and disease. Genes (Basel). 2017;8(12)353.

10.

Greene

Baird

Brady

Lim

Gray

McDermott

Finn

. Circular RNAs: biogenesis, function and role in human diseases. Front Mol Biosci. 2017;4:38.

11.

Militello

Weirick

John

Doring

Dimmeler

Uchida

. Screening and validation of lncRNAs and circRNAs as miRNA sponges. Brief Bioinform. 2017;18(5):780–788.

12.

Ghali

MGZ

. Role of the medullary lateral tegmental field in sympathetic control. J Integr Neurosci. 2017;16(2):189–208.

13.

Yin

Sui

Meng

Jiang

. The omega-3 polyunsaturated fatty acid docosahexaenoic acid inhibits proliferation and progression of non-small cell lung cancer cells through the reactive oxygen species-mediated inactivation of the PI3 K /Akt pathway. Lipids Health Dis. 2017;16(1):87.

14.

Taborda

Ramirez

Bernal

. Circular RNAs in colorectal cancer: possible roles in regulation of cancer cells. World J Gastrointest Oncol. 2017;9(2):62–69.

15.

Huang

Zheng

Chen

Song

Zhou

Tang

Huang

. Comprehensive circular RNA profiling reveals the regulatory role of the circRNA-100338/miR-141-3p pathway in hepatitis B-related hepatocellular carcinoma. Sci Rep. 2017;7(1):5428.

16.

Chen

Yao

Ying

Guo

. Hsa_circ_0005986 inhibits carcinogenesis by acting as a miR-129-5p sponge and is used as a novel biomarker for hepatocellular carcinoma. Oncotarget. 2017;8(27):43878–43888.

17.

Wang

Yang

Zhang

Sun

Yang

Zhou

. Circular RNA cSMARCA5 inhibits growth and metastasis in hepatocellular carcinoma. J Hepatol. 2018;68(6):1214–1227.

18.

Chen

Liu

Feng

Wang

Bai

Zhao

Shen

Wang

Yang

, et al Circ-ANAPC7 is upregulated in acute myeloid leukemia and appears to target the mir-181 family. Cell Physiol Biochem. 2018;47(5):1998–2007.

19.

Lin

Chen

. Identification of potentially functional CircRNA-miRNA-mRNA regulatory network in hepatocellular carcinoma by integrated microarray analysis. Med Sci Monit Basic Res. 2018;24:70–78.

20.

Lagos-Quintana

Rauhut

Lendeckel

Tuschl

. Identification of novel genes coding for small expressed RNAs. Science. 2001;294(5543):853–858.

21.

Tay

Rinn

Pandolfi

. The multilayered complexity of ceRNA crosstalk and competition. Nature. 2014;505(7483):344–352.

22.

Salmena

Poliseno

Tay

Kats

Pandolfi

. A ceRNA hypothesis: the rosetta stone of a hidden RNA language?. Cell. 2011;146(3):353–358.

23.

Kulcheski

Christoff

Margis

. Circular RNAs are miRNA sponges and can be used as a new class of biomarker. J Biotechnol. 2016;238:42–51.

24.

Rong

Sun

Liu

Dong

Tang

Cao

. An emerging function of circRNA-miRNAs-mRNA axis in human diseases. Oncotarget. 2017;8(42):73271–73281.

25.

Xiong

Dang

Lin

Wen

Luo

Feng

Chen

. A circRNA-miRNA-mRNA network identification for exploring underlying pathogenesis and therapy strategy of hepatocellular carcinoma. J Transl Med. 2018;16(1):220.

26.

Bai

Peng

Qiu

Lyu

Zhang

Tao

Wang

. circFBLIM1 act as a ceRNA to promote hepatocellular cancer progression by sponging miR-346. J Exp Clin Cancer Res. 2018;37(1):172.

27.

Huang

Peng

Zhou

Chen

Huang

Tang

. Circular RNA 101368/miR-200a axis modulates the migration of hepatocellular carcinoma through HMGB1/RAGE signaling. Cell Cycle. 2018;17(19-20):2349–2359.

28.

Liu

Shu

Wang

. MicroRNA-1297 regulates hepatocellular carcinoma cell proliferation and apoptosis by targeting EZH2. Int J Clin Exp Pathol. 2015;8(5):4972–4980.

29.

Liu

Liang

Jiang

. MiR-1297 promotes apoptosis and inhibits the proliferation and invasion of hepatocellular carcinoma cells by targeting HMGA2. Int J Mol Med. 2015;36(5):1345–1352.

30.

Riento

Ridley

. Rocks: multifunctional kinases in cell behaviour. Nat Rev Mol Cell Biol. 2003;4(6):446–456.

31.

Ding

Tan

Zhao

Jiang

Zhang

Wang

. MiR-145 suppresses cell proliferation and motility by inhibiting ROCK1 in hepatocellular carcinoma. Tumour Biol. 2016;37(5):6255–6260.

32.

Zhan

Zheng

Teng

Bao

Liu

Zhang

Guo

Ding

Wang

. MiR-199a/b-5p inhibits hepatocellular carcinoma progression by post-transcriptionally suppressing ROCK1. Oncotarget. 2017;8(40):67169–67180.