The antiphospholipid syndrome, now 13 years old, embraces almost all specialties. After a slow start—possibly because many early descriptions were published largely in the rheumatology literature, the syndrome has become recognised worldwide as a major cause of venous-arterial thrombosis, strokes, valvular disease and recurrent abortion. Its prevalence may soon overtake that of its ‘parent’ disease, Lupus.
KhamashtaMAAshersonRA. Hughes syndrome: Antiphospholipid antibodies move closer to thrombosis in 1994. Br J Rheumatol1995; 34: 493–497
2.
WilsonWHughesGRV. Aetiology of Jamaican Neuropathy. Lancet1975; i: 240
3.
HughesGRV. The anticardiolipin syndrome. Clin Exp Rheumatol1985; 3: 285–286
4.
HarrisENHughesGRVGharavAE. The antiphospholipid antibody syndrome. J. Rheumatol. 1987; Suppl 13, 210
5.
MackworthYoung CGDavidJLoizouSWalportMJ. Primary antiphospholipid syndrome: features of patients with raised anticardiolipin antibodies and no other disorder. Br J Rheumatol1987; 26 (Suppl 2): 94
6.
AshersonRAThe primary antiphospholipid syndrome: major clinical and serological features. Medicine (Baltimore)1989; 89: 366–374
