A comparison of five health status instruments in patients with systemic lupus erythematosus (SLE)

Abstract

The aim of the present investigation was to assess and compare health status instruments in SLE. One hundred and twenty-five patients completed five health status instruments: the Health Assessment Questionnaire (HAQ), Functional Ability Index, the Fatigue Severity Scale (FSS), the Disability Days Measure (DDM), the Centre for Epidemiological Studies- Depression Scale (CES-D), and the Medical Outcomes Study (MOS) Short Form Health Survey during their Clinic visit. Disease activity was measured using the SLE Disease Activ ity Index (SLEDAI).

All instruments described a spectrum of quality of life outcomes in these patients. An inter-instrument correlation analysis revealed that components of the MOS correlated sig nificantly with each of the other instruments used. There was no correlation between any of the instruments used and the SLEDAI.

We conclude that health status assessment as measured by the MOS short form is a valid independent outcome measure in patients with SLE.

Keywords

Systemic lupus erythematosus Health status Disease activity

Get full access to this article

View all access options for this article.

References

Fessel WJ Systemic lupus erythematosus in the. community. Arch Intern Med 1974; 134: 1027-1035.

Michet CJ et al Epidemiology of systemic lupus erythematosus and other connective tissue diseases in Rochester, Minnesota, 1950-1979. Mayo Clin Proc 1985; 60: 105-113.

Hochberg MC Systemic lupus erythematosus. Rheum Dis Clin North Am 1990; 16: 617-639.

Hopkinson ND , Doherty M. , Powell RJ Clinical features and race-specific incidence/prevalence rates of systemic lupus erythematosus in a geographically complete cohort of patients. Ann Rheum Dis 1994; 53: 675-680.

Gladman DD Indicators of disease activity, prognosis and treatment of systemic lupus erythematosus. Curr Opin Rheumatol 1994 ; 6: 487-492.

Bombardier C. et al (inc. The Committee on Prognosis Studies in SLE). The development and validation of the SLE Disease Activity Index (SLEDAI). Arthritis Rheum 1992; 35: 630-640.

Liang MH The historical and conceptual framework for functional assessment in rheumatic disease. J Rheumatol 1987; 14 (Suppl. 14): 2-5.

Glossary Committee , American College of Rheumatology. Dictionary of the Rheumatic Diseases. Volume III: Health Status Measurement. Contact Associates: New York; 1988.

Fries JF , Spitz P. , Kraines RG , Holman H. Measurement of patient outcome in arthritis. Arthritis Rheum 1980; 23: 137-145.

10.

Meenan RF , Gertman PM , Mason JH Measuring health status in arthritis: the Arthritis Impact Measurement Scale . Arthritis Rheum 1980; 23: 146-152.

11.

Brown JH et al The dimensions of health outcomes: A cross-validated examination of health status measurement. Am J Public Health 1094; 74: 159-161.

12.

Brook RH et al Overview of adult health status measures fielded in Rand's Health Insurance study. Med Care 1979; 17 (Suppl. 7): 1-131.

13.

Stewart AL , Hays RD , Ware JE The MOS short-form general health survey: reliability and validity in a patient population. Med Care 1988; 26: 724-735.

14.

Wachtel T. et al Quality of life in persons with Human Immunodeficiency Virus infection: measurement by the Medical Outcomes Study instrument. Ann Int Med 1992; 116: 129-137.

15.

Hochberg MC , Sutton JD Physical disability and psychosocial dysfunction in systemic lupus erythematosus. J Rheumatol 1988; 15: 959-964.

16.

Krupp LB , LaRocca NG , Muir J. , Steinberg AD A study of fatigue in systemic lupus erythematosus. J Rheumatol 1990; 17: 1450-1452.

17.

Radloff LS CES-D Scale: a self-report depression scale for research in the general population . Appl Psychol Mec 1977; 4: 385-401.

18.

Foud M. , Petri M. , Goldman D. Health status in systemic lupus erythematosus (SLE): a case-control study . Arthritis Rheum 1993; 36 (Suppl. 9): S69.

19.

Milligan SE et al An assessment of the Health Assessment Questionnaire Functional Ability Index among women with systemic lupus erythematosus . J Rheumatol 1993; 20: 972-976.

20.

Burckhardt CS , Archenholtz B. , Bielle A. Quality of life of women with systemic lupus erythematosus: a comparison with women with rheumatoid arthritis. J Rheumatol 1993; 20: 977-981.

21.

Callahan LF , Smith WJ , Pincus T. Self-report questionnaires in five rheumatic diseases. Arthritis Care Res 1989; 2: 122-131.