Laboratory detection of antiphospholipid antibodies

Abstract

'Antiphospholipid' (aPL) antibodies are a heterogenous group of autoantibodies that are now considered to be directed mainly to plasma proteins or protein-phospholipid complexes¹. Standardisation of assays for anticardiolipin (aCL) antibodies and lupus anti coagulants (LA) have been fraught with difficulty despite numerous attempts to perform this by International Standardisation Workshops and Committees.

Keywords

antiphospholipid antibodies lupus anticoagulants β2-glycoprotein I

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References

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