Benign intracranial hypertension is a rare complication of systemic lupus erythematosus often attributed to cerebral sinus thrombosis which impairs venous drainage and cerebrospinal fluid outflow. We report the case of a woman with a primary antiphospholipid syndrome who developed benign intracranial hypertension with no actual evidence of venous cerebral thrombosis and with no other possible cause for this clinical manifestation than high titres of anticardiolipin antibodies and a lupus anticoagulant.
Kaplan RE et al. Pseudotumor cerebri associated with cerebral venous sinus thrombosis, internal jugular venous thrombosis and systemic lupus erythematosus. J Pediatr1985; 107: 266-268.
5.
Shiozawa Z. et al. Superior sagittal sinus thrombosis and systemic lupus erythematosus . Ann Neurol1986; 20: 272-273.
6.
Parnass SM et al. Dural sinus thrombosis: a mechanism for pseudomotor cerebri in systemic lupus erythematosus. J Rheumatol1987; 14: 152-155.
7.
Li EK, Ho Pcp.Pseudotumor cerebri in systemic lupus erythematosus. J Rheumatol1989; 16: 113-116.
8.
EK, LiMSYC, Chan.Is pseudotumor cerebri in systemic lupus erythematosus a thrombotic event?J Rheumatol1990; 17: 983-984.
9.
Mortifee Prs , Bebb RA, Stein H.Communicating hydrocephalus in systemic lupus erythematosus with antiphospholipid antibody syndrome. J Rheumatol1992; 19: 1299-1302.
10.
Mokri B., Jack JC, Petty GWPseudotumor syndrome associated with cerebral venous sinus occlusion and antiphospholipid antibodies. Stroke1993 ; 24: 469-472.
11.
Marcelis J. , Silberstein SDIdiopathic intracranial hypertension without papilledema. Arch Neurol1991; 48: 392-399.
12.
Weisberg LA , Chutorian AMPseudotumor cerebri of childhood . Am J Dis Child1977; 131: 1243-1248.
13.
Vachvanichsanong P., Dissaneewate P., Vasikananont P.Pseudotumor cerebri in a boy with systemic lupus erythematosus. Am J Dis Child1992; 146: 1417-1419.
14.
Delgiudice GC et al. Pseudotumor cerebri and childhood systemic lupus erythematosus. J Rheumatol1986; 13: 748-752.
Hill MB et al. Characterization and specificity of antiendothelial cell membrane antibodies and their relationship to thrombosis in the primary antiphospholipid syndrome. Lupus1994; 3: 333 (abstract no. 83).
17.
Herranz MT et al. Association between antiphospholipid antibodies and epilepsy in patients with SLE. Arthritis Rheum1994 ; 37: 568-571.
18.
Asherson RA et al. Chorea in systemic lupus and lupus-like disease: association with antiphospholipid antibodies. Semin Arthritis Rheum1987; 16: 253-259.
19.
Alarcon-Segovia D. et al. Antiphospholipid antibodies and the antiphospholipid syndrome in SLE: a prospective analysis of 500 consecutive patients. Medicine (Balt)1989; 68: 353-356.
