Role of the Biologics in Autoimmunity

Abstract

Get full access to this article

View all access options for this article.

References

Lee B. , Ciardelli TL Clinical applications of cytokines for immunostimulation and immunosuppression . Prog Drug Res 1992; 39: 167-96.

Kroemer G. , de Alboran IM , Gonzalo JA , Martinez AC Immunoregulation by cytokines. Crit Rev Immunol 1993; 13: 163-91.

Balkwill FR , Burke F. The cytokine network. Immunol Today 1989; 10: 299-304.

Aulitzky WE , Huber C. , Peschel C. Cytokine therapy of neoplastic and inflammatory disease. Int Arch Allergy Immunol 1993; 101: 221-6.

Dianzani F. Biological basis for the clinical use of interferon. Gut 1993; 34 (Suppl.): S74-6.

Daniels HM , Meager A. , Eddleston Alw , Alexander Gjm , Williams R. Spontaneous production of tumour necrosis factor-α and interleukin-Iβ during interferon-α treatment of chronic HBV infection. Lancet 1990; 335: 875-7.

Stadler R. , Ruszczak A. Interferons: new additions and indications for use. Dermatol Clin 1993; 11: 187-99.

Hansen RM , Borden EC Current status of interferons in the treatment of cancer. Oncology 1992; 6: 19-29.

Lejeune F. , Bauer J. , Leyvraz S. , Leinard D. Disseminated melanoma, preclinical studies, clinical trials and patient treatment . Curr Opin Oncol 1993; 5: 390-6.

10.

Wirth MP Immunotherapy for metastatic renal cell carcinoma. Urologic Clin N Am 1993; 20: 283-95.

11.

Hill Adk , Redmond HP , Croke DT , Grace PA , Bouchier-Hayes D. Cytokines in tumour therapy. Br J Surg 1992 ; 79: 990-7.

12.

Lotze MT , Rubin JT , Zeh HJ New biologic agents come to bat for cancer therapy. Curr Opin Oncol 1992; 4: 1116-23.

13.

Brunda MJ , Luistro L. , Warrier RR et al. Antitumour and antimetastatic activity of interleukin 12 against murine tumours. J Exp Med 1993; 178: 1223-30.

14.

Lemmel EM , Gaus W. , Hofschneider PH Multicenter double-blind trial of interferon-γ versus placebo in the treatment of rheumatoid arthritis. Arthritis Rheum 1991 ; 34: 1621-2.

15.

Cannon GW , Emkey RD , Denes A. Prospective two-year follow-up of recombinant interferon-γ in rheumatoid arthritis. J Rheumatol 1990; 17: 304-10.

16.

Shiozawa S. , Shiozawa K. , Kita M. , Kitshida T. , Fujita T. , Imura S. A preliminary study on the effect of alpha-interferon treatment on the joint inflammation and serum calcium in rheumatoid arthritis . Br J Rheumatol 1992; 31: 405-8.

17.

Panitch HS , Bever CT Clinical trials of interferons in multiple sclerosis: what have we learned ? J Neuroimmunol 1993; 46: 155-64.

18.

Fentiman IS , Thomas BS , Balkwill FR , Rubens RD , Hayward JL Primary hypothyroidism associated with interferon therapy of breast cancer. Lancet 1985; 1: 1166 (letter).

19.

Burman P. , Karlsson FA , Oberg K. , Alm G. Autoimmune thyroid disease in interferon-treated patients. Lancet 1985; 2: 100-1 (letter).

20.

Fentiman IS , Balkwill FR , Thomas BS , Russel MJ , Todd I. , Bottazo GF An autoimmune aetiology for hypothyroidism following interferon treatment for breast cancer. Eur J Cancer Clin Oncol 1988; 24: 1299-1303.

21.

Ronnblom LE , Alm GV , Oberg KE Autoimmunity after alpha-interferon therapy for malignant carcinoid tumours. Ann Intern Med 1991; 115: 178-83.

22.

Burman Pia , Totterman The , Oberg K. , Karlsson FA Thyroid autoimmunity in patients on long term therapy with leukocyte-derived interferon. J Clin Endocrin Metab 1986; 63: 1086-90.

23.

Gisslinger H. , Gilly B. , Woloszczuk W. et al. Thyroid autoimmunity and hypothyroidism during long-term treatment with recombinant interferon-alpha. Clin Exp Immunol 1992; 90: 363-7.

24.

Mayet W-J. , Hess G. , Gerken G. et al. Treatment of chronic type B hepatitis with recombinant α-interferon induced autoantibodies not specific for autoimmune chronic hepatitis. Hepatology 1989; 10: 24-8.

25.

Atkins MB , Mier JW , Parkinson DR , Gould JA , Berkman EM , Kaplan MM Hypothyroidism after treatment with interleukin 2 and lymphokine activated killer cells. New Engl J Med 1988; 318: 1557-63.

26.

Van Lissum PA , de Muler Phm , Mattijssen Ejm , Corstens Fhm , Wagner Djth. Hypothyroidism and goitre during interleukin-2 therapy without LAK cells. Lancet 1989; 1: 224 (letter).

27.

Hoekman K. , von Blomberg-van der Flier BM , Wagstaff J. , Drexhage HA , Pinedo HM Reversible thyroid dysfunction during treatment with GM-CSF. Lancet 1991; 2: 541-2.

28.

Conlon KC , Urba WJ , Smith JW , Steis RG , Longo DL , Clark JW Exacerbation of symptoms of autoimmune disease in patients receiving alpha-interferon therapy. Cancer 1990; 65: 2237-42.

29.

Hazenberg Bpc , van Leeuwen MA , van Rijswik MH , Stem AC , Vellenga E. Correction of granulocytopenia in Felty's syndrome by granulocyte-macrophage colony-stimulating factor. Simultaneous induction of interleukin-6 release and flare-up of arthritis. Blood 1989; 74:2769-70.

30.

Wandl UB , Nagel-Hiemke M. , May D. et al. Lupus-like autoimmune disease induced by interferon therapy for myeloproliferative disorders. Clin Immunol Immunopath 1992; 65: 70-4.

31.

Ehrenstein MR , McSweeney E. , Swana M. , Worman CP , Goldstone AH , Isenberg DA Appearance of anti-DNA antibodies in patients treated with interferon-α. Arthritis Rheum 1993; 36: 279-80.

32.

Fattovich G. , Betterle C. , Brollo L. , Giustina G. , Pedini B. , Alberti A. Induction of autoantibodies during alpha interferon treatment in chronic hepatitis B. Arch Virol 1992; 4 (Suppl.): 291-3.

33.

McLaughlin P. , Talpaz M. , Quesada JG , Saleem A. , Barlogie B. , Gutterman JU Immune thrombocytopenia following α-interferon therapy in patients with cancer. JAMA 1985 ; 254: 1352-4.

34.

Akard LP , Hoffman R. , Elias L. , Saiers JH Alpha-intcrferon and immune hemolytic anemia. Ann Intern Med 1986; 105: 306 (letter).

35.

Stricker RB , Barlogie B. , Kiprov DD Acquired factor VIII inhibitor associated with chronic interferon-α therapy. J Rheum 1994; 21: 350-2.

36.

Karlsson-Parra A. , Burman P. , Hagberg H. et al. Autoantibodies to epithelial cells in patients on long-term therapy with leucocyte-derived interferon-α. Clin Exp Immunol 1990; 81: 72-5.

37.

Williams WM , Ehrenstein MR , Isenberg DA The background to autoimmunity. In: Immunopharmacology of Joints and Connective Tissue. Davies ME , Dingle JT (eds). London: Academic Press, 1994: 1-34.

38.

Brennan DC , Yui MA , Wuthrich RP , Kelley VE Tumor necrosis factor and IL-1 in New Zealand Black/White mice. J Immunol 1989; 143: 34-70.

39.

Jacob CO , McDevitt HO. Tumour necrosis factor-α in murine autoimmune 'lupus' nephritis . Nature 1988; 331: 356-8.

40.

Kim T. , Kanayama Y. , Negoro N. , Okamura M. , Takeda T. , Inoue T. Serum levels of interferons in patients with systemic lupus erythematosus . Clin Exp Immunol 1987; 70: 562-9.

41.

Ytterberg SR , Schnitzer TJ Serum interferon levels in patients with systemic lupus erythematosus. Arthritis Rheum 1982; 25: 401-6.

42.

Bacon TH , deVere-Tyndall A. , Tyrell Daj , Denman AM , Ansell BM Interferon system in patients with systemic juvenile chronic arthritis in vivo and in vitro studies. Clin Exp Immunol 1983; 54: 23-30.

43.

Houssiau FA , Devogelaer J-P. , van Damme J. , de Deuxchaisnes CN , van Snick J. Interleukin-6 in synovial fluid and serum of patients with rheumatoid arthritis and other inflammatory arthritides. Arthritis Rheum 1988; 31: 784-8.

44.

Ciampolillo A. , Mirakian R. , Schultz T. et al. Retrovirus-like sequences in Graves' disease: implications for human autoimmunity. Lancet 1989; 1: 1096-1100.

45.

Schattner A. , Duggan D. , Naparstek Y. , Schwartz RS Effects of interferon-α on the expression of a lupus idiotype in normal humans. Clin Immunol Immunopath 1986; 38: 327-36.

46.

Isenberg DA , Shoenfeld Y. , Madaio MP et al. Anti-DNA antibody idiotypes in systemic lupus erythematosus. Lancet 1984; 2: 417-22.

47.

Rosa F. , Fellous M. The effect of gamma interferon on MHC antigens. Immunol Today 1984; 5: 261-2.

48.

Sztein MB , Steeg PS , Johnson HM , Oppenheim JJ Regulation of human peripheral blood monocyte DR antigen expression in vitro by lymphokines and recombinant interferons. J Clin Invest 1984; 73: 556-65.

49.

Hanfusa T. , Pujol-Borrel R. , Chiovato L. , Russel Rcg , Doniach D. , Bottazo GF Aberrant expression of HAL-DR antigen on thyrocytes in Graves' disease: elevance for autoimmunity. Lancet 1983; 2: 1111-5.

50.

Selby WS , Janossy G. , Mason DY , Jewell DP Expression of HLA-DR antigens by colonic epithelium in inflammatory bowel disease. Clin Exp Immunol 1983 ; 53: 614-26.

51.

Foulis A. , Farquharson MA Aberrant expression of HLA-DR antigens by insulin-containing B cells in recent onset type I (insulin-dependent) diabetes mellitus. Diabetes 1986; 35: 1215-24.

52.

Lucas-Martin AL , Foz-Sala M. , Todd I. , Bottazo GF , Pujol-Borrel R. Occurrence of thyrocyte HLA class II expression in a wide variety of thyroid diseases: relationship with lymphocytic infiltration and thyroid autoantibodies. J Clin Endocrinol Metab 1988; 66: 367-75.

53.

Bottazo GF , Pujol-Borrel R. , Hanafusa T. , Feldmann M. Hypothesis: role of aberrant HLA-DR expression and antigen presentation in the induction of endocrine autoimmunity. Lancet 1983; 2: 1115-18.

54.

Hibi T. , Ohara M. , Watanabe M. et al. Interleukin 2 and interferon-γ augment anticolon antibody dependent cellular cytotoxicity in ulcerative colitis. Gut 1993; 34: 788-93.

55.

Trincheri D. , Santoli D. , Koprowski H. Spontaneous cell-mediated cytotoxicity in humans; role of interferon and immunoglobulins. J Immunol 1978; 120: 1849-56.

56.

Levinson AI , Dziarski A. , Hooks JJ Modulation of polyclonal B cell differentiation by human leukocyte alpha interferon. Clin Exp Immunol 1982; 49: 677-83.

57.

Fridman WH , Gresser I. , Bandu MT , Aguet M. , Neauport-Sautes C. Interferon enhances the expression of Fcγ-receptors. J Immunol 1980; 124:2436-41.

58.

Steis RG , Smith II JW , Urba WJ Resistance to recombinant interferon alpha-2a in hairy-cell leukaemia associated with neutralizing anti-interferon antibodies. New Engl J Med 1988; 318: 1409-13.

59.

Elliott MJ , Maini RN , Feldmann M. et al. Treatment of rheumatoid arthritis with chimeric monoclonal antibodies to tumor necrosis factor α. Arthritis Rheum 1993; 36: 1681-90.