Antiphospholipid Antibodies Eicosanoids

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Carreras LO , Defreyn G. , Machin SJ et al. Recurrent arterial thrombosis, repeated intrauterine death and 'lupus' anticoagulant. Detection of immunoglobulin interfering with prostacyclin formation. Lancet 1981; 1: 244-6.

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Carreras LO , 'Vermylen JG 'Lupus' anticoagulant and thrombosis. Possible role of inhibition of prostacyclin formation. Thromb Haemos 1982 ; 48: 38-40.

De Wolf F. , Carreras LO , Moerman P. , Vermylen J. , van Assche A. , Renaer M. Decidual vasculopathy and extensive placental infarction in a patient with repeated thromboembolic accidents, recurrent fetal loss and a lupus anticoagulant . Am J Obstet Gynecol 1982; 142: 829-34.

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Watson KV , Schorer AE Lupus anticoagulant inhibition of in vitro prostacyclin release is associated with a thrombosis-prone subset of patients. Am J Med 1991; 90: 47-53.

Schorer AE , Duane PG , Woods VL , Niewoehner DE Some antiphospholipid antibodies inhibit phospholipase A2 activity . J Lab Clin Med 1992; 120: 67-77.

Rustin Mha , Bull HA , Machin SJ , Isenberg DA , Snaith ML , Dowd PM Effects of the lupus anticoagulant in patients with systemic lupus erythematosus on endothelial cell prostacyclin release and procoagulant activity. J Invest Dermatol 1988; 90: 744-8.

Coade SB , van Haaren E. , Loizou S. , Walport MJ , Denman AM , Pearson JD Endothelial prostacyclin release in systemic lupus erythematosus. Thromb Haemos 1989; 61: 97-100.

Dudley DJ , Mitchell MD , Branch DW Pathophysiology of antiphospholipid antibodies: absence of prostaglandin-mediated effects on cultured endothelium. Am J Obset Gynecol 1990; 162: 953-8.

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Petraiuolo W. , Bovill E. , Hoak J. The lupus anticoagulant stimulates the release of prostacyclin from human endothelial cells. Thromb Res 1988; 50:847-55.

Walker TS , Triplett DA , Javed N. , Musgrave K. Evaluation of lupus anticoagulants: antiphospholipid antibodies, endothelium-associated immunoglobulin, endothelial prostacyclin secretion and antigenic protein S levels. Thromb Res 1988; 51: 267-81.

Hasselaar P, Derksen RHWM, Blokzijl L, de Groot PG. Thrombosis associated with antiphospholipid antibodies cannot be explained by effects on endothelial and platelet prostanoid synthesis. Thromb Haemost 1988; 59: 80-5.

Lindsey N. , Henderson F. , Malia R. , Greaves M. , Hughes P. Serum masks the inhibition of thrombin-induced prostacyclin release produced by anticardiolipin antibodies. Br J Rheumatol 1992; 31: 179-83.

Lellouche F. , Martinuzzo M. , Said P. , Maclouf J. , Carreras LO Imbalance of thromboxane/prostacyclin biosynthesis in patients with lupus anticoagulant . Blood 1991; 78: 2894-9.

Catella F. , Healy D. , Lawson JA , FitzGerald GA 11-dehydrothromboxane B2: a quantitative index of thromboxane A2 formation in the human circulation. Proc Natl Acad Sci USA 1986; 83: 5861-5.

Arfors L. , Vestergvist O. , Johnsson H. , Grien K. Increased thromboxane formation in patients with antiphospholipid syndrome . Eur J Clin Invest 1990; 20: 607-12.

Violi F. , Davi G. , Ferro D. , Valesini G. , Iuliano L. , Leo R. , Patrono C. Thromboxane biosynthesis in patients with systemic lupus erythematosus . Thromb Haemost 1993; 69: 541 (abstract).

Lellouche F. , Falcón C. , Carreras L. , Maclouf J. Selective inhibition of platelet-derived thromboxane A2 in patients with lupus anticoagulant using low doses aspirin as assessed by enzyme immunoassay. In: Advances in Prostaglandins, Thromboxane and Leukotrienes Research , vol. 21, pp. 611-14. Samuelsson B , Ramwell PW , Paoletti R , Folco G , Granstrom E (eds). New York, Raven Press, 1990.

Martinuzzo ME , Maclouf J. , Carreras LO , Lévy Toledano S. Antiphospholipid antibodies enhance thrombin-induced platelet activation and thromboxane formation . Thromb Haemost 1993; 70: 667-71.

Lin YL , Wang CT Activation of human platelets by the rabbit anticardiolipin antibodies. Blood 1992; 80: 3135-43.

Lockshin MD , Druzin ML , Qamar T. Prednisone does not prevent recurrent fetal death in women with antiphospholipid antibodies. Am J Obstet Gynecol 1989; 160: 439-43.

FitzGerald GA , Smith B. , Pederson AK , Brash AR Increased prostacyclin biosynthesis in patients with severe atherosclerosis and platelet activation . New Engl J Med 1984; 310: 1065-8.

Fitzgerald DJ , Roy L. , Catella F. , FitzGerald GA Platelet activation in unstable coronary disease . New Engl J Med 1986; 315: 983-9.

Reilly Iag , Roy L. , FitzGerald GA Biosynthesis of thromboxane in patients with systemic sclerosis and Raynaud's phenomenon. Br Med J 1986; 292: 1037-9.

Carreras LO , Vermylen J. Antiphospholipid antibodies and impairment of prostacyclin synthesis by endothelium . In Phospholipid Binding Antibodies, pp. 231-245. Haris EN , Exner T , Hughes GRV , Asherson RA (eds). Boca Raton, Florida: CRC Press, 1991.

Carreras LO , Maclouf J. The lupus anticoagulant and eicosanoids. Prostaglandins Leukotrienes and Essential Fatty Acids 1993 ; 49: 483-8.