Cofactors Involved in the Antiphospholipid Syndrome

Loeliger A. Prothrombin as co-factor of the circulating anticoagulant in systemic lupus erythematosus? Thrombos Diathes Haemorrh (Stuttg) 1959; 3: 237-56.

Yin ET , Gaston LW Purification and kinetic studies on a circulating anticoagulant in a suspected case of lupus erythematosus. Thrombos Diathes Haemorrh (Stuttg) 1965; 14: 88-115.

Rivard GE , Schiffman S. , Rapaport SI Cofactor of the 'lupus anticoagulant'. Thrombos Diathes Haemorrh (Stuttg) 1974; 32: 554-63.

Exner T. , Rickard KA , Kronenberg H. A sensitive test demonstrating lupus anticoagulant and its behavioural patterns . Br J Haematol 1978; 40: 143-51.

McNeil HP , Simpson RJ , Chesterman CN , Krilis SA Antiphospholipid antibodies are directed against a complex antigen that includes a lipid-binding inhibitor of coagulation: β2-glycoprotein I (apolipoprotein H). Proc Natl Acad Sci USA 1990; 87: 4120-4.

Galli M. , Comfurius P. , Maassen C. et al. Anticardiolipin antibodies (ACA) are directed not to cardiolipin but to a plasma protein cofactor. Lancet 1990 ; 335: 1544-7.

Matsuura E. , Igarashi Y. , Fujimoto M. , Ichikawa K. , Koike T. Anticardiolipin cofactor(s) and differential diagnoses of autoimmune disease . Lancet 1990; 336: 177-8.

Bevers EM , Galli M. β2-glycoprotein I for binding of anticardiolipin antibodies to cardiolipin . Lancet 1990; 336: 952-3.

Loizou S. , McCrea JD , Rudge AC et al. Measurement of anticardiolipin antibodies by an enzyme-linked immunosorbent assay: standardization and quantitation of results. Clin Exp Immunol 1985; 62: 738-44.

Harris EN , Pierangeli S. , Barquinero J. , Ordi-Ros J. Anticardiolipin antibodies and binding of anionic phospholipids and serum protein. Lancet 1990; 336: 505-6.

Harris EN , Pierangeli S. What is the 'true' antigen for antiphospholipid antibodies? Lancet 1990; 336: 1505.

Proceedings of the workshop on β2-glycoprotein I, October 1991, Milan. Clin Exp Rheum (in press).

Chamley LW , McKay EJ , Pattison NS Cofactor dependent and cofactor independent anticardiolipin antibodies. Thromb Res 1991; 61: 291-9.

Schousboe I. Characterization of the interaction between β2-glycoprotein I and mitochondria, platelets, liposomes and bile acids. Int J Biochem 1983; 15: 1393-1401.

Lozier J. , Takahashi N. , Putnam FW Complete amino acid sequence of human plasma beta 2-glycoprotein I. Proc Natl Acad Sci USA 1984; 81: 3640-4.

Steinkasserer A. , Estaller C. , Weiss EH , Sim RB Complete nucleotide and deduced amino acid sequence of human β2-glycoprotein I. Biochem J 1991; 277: 387-91 .

Kroll J. , Larsen JK , Loft H. et al. DNA-binding proteins in Yoshida ascites tumor fluid. Biochim Biophys Acta 1976; 434: 490-501.

Polz E. Isolation of a specific lipid binding protein from human serum by affinity chromatography using heparin-sepharose. In: Peeters H , ed. Protides of Biological Fluids. Oxford: Pergamon Press, 1979: 817-20.

Schousboe I. Addition of deoxycholate in electroimmunoassay and crossed immunofocusing for quantification of β2-glycoprotein I and its subfractions. J Biochem Biophys Meth 1982 ; 6: 105-14.

Schousboe I. Binding of β2-glycoprotein I to platelets: effect on adenylate cyclase activity. Thromb Res 1980; 19: 225-37.

Nimpf J. , Wurm H. , Kostner GM Interaction of β2-glycoprotein I with human platelets: influence upon the ADP-induced aggregation. Thromb Haem 1985 ; 54: 397-401 .

Schousboe I. , Rasmussen MS The effect of β2-glycoprotein I on the dextran sulfate and sulfatide activation of the contact system (Hageman system) in the blood coagulation. Int J Biochem 1988; 20: 787-92.

Nimpf J. , Bevers EM , Bomans PH , Till U. , Kostner GM , Zwaal Rfa. Prothrombinase activity of human platelets is inhibited by β2-glycoprotein I. Biochim Biophys Acta 1986; 884: 142-9.

Exner T. , Sahman N. , Trudinger B. Separation of anticardiolipin antibodies from lupus anticoagulant on a phospholipid polystyrene column. Biochem Biophys Res Commun 1988; 155: 1001-7.

McNeil HP , Chesterman CN , Krilis SA Anticardiolipin antibodies and lupus anticoagulants comprise antibody subgroups with different phospholipid binding characteristics. Br J Haematol 1989; 73: 506-13.

Bevers EM , Galli M. , Barbul T. , Comfurius P. , Zwaal Rfa. Lupus anticoagulant IgG's (LA) are not directed to phospholipids only, but to a complex of lipid-bound human prothrombin. Thromb Haemost 1991; 66: 629-32.

Bevers EM , Comfurius P. , Zwaal Rfa. Platelet procoagulant activity: physiological significance and mechanisms of exposure. Blood Reviews 1991; 5: 146-54.