The association of outer foveal microdefect and LES or hydroxychloroquine use has not been established in current literature.
Case report
We present the first reported case of bilateral outer foveal microdefect ina a patient with systemic lúpus erythematosus using hydroxycloroquine.
Discussion/conclusion
While it is not possible to definitively attribute the described findings in our patient to HCQ use, it is important to be aware of the possibility that the outer foveal microdefect may be caused by this medication. Therefore, patients on chronic HCQ therapy should be informed about the risk of potential visual adverse effects, so that appropriate interventions can be implemented if necessary.
ChandranKGiridharAGayathriMS, et al. (2023). Outer foveal defects in TYPE-2 macular telangiectasia. Retina, 43(1), 111–119. DOI: 10.1097/IAE.0000000000003640.
3.
SinghSRVaidyaHBorrelliE, et al. (2023). Foveal photoreceptor disruption in ocular diseases: an optical coherence tomography-based differential diagnosis. Surv Ophthalmol, S0039-6257(23)00046-00052. DOI: 10.1016/j.survophthal.2023.03.003.
4.
MarmorMFKellnerULaiTYAmerican Academy of Ophthalmology, et al. (2016). Recommendations on screening for chloroquine and hydroxychloroquine retinopathy (2016 revision). Ophthalmology, 123(6), 1386–1394. DOI: 10.1016/j.ophtha.2016.01.058.
