We report the case of a Caucasian man with systemic lupus erythematosus who had recurrent fevers and abdominal pain. He was later found to carry E148Q polymorphism of MEFV, the gene responsible for familial Mediterranean fever.
1 Sultan SM Ioannou Y Isenberg DA . A review of gastrointestinal manifestations of systemic lupus erythematosus.Rheumatology (Oxford)1999; 38: 917 – 932 .
2.
2 Sohar E Gafni J Pras M Heller H . Familial Mediterranean fever. A survey of 470 cases and review of the literature.Am J Med1967; 43: 227 .
3.
3 Ozen S Bakkaloglu A . C reactive protein: protecting from lupus in familial Mediterranean fever.Ann Rheum Dis.2005; 64: 786 – 787 .
4.
4 Booth DR Lachmann HJ Gillmore JD Booth SE Hawkins PN . Prevalence and significance of the familial Mediterranean fever gene mutation encoding pyrin Q148.QJM2001; 94: 527 – 531 .