1 Jury ECIsenberg DAMauri CEhrenstein MR . Atorvastatin restores Lck expression and lipid raft-associated signaling in T cells from patients with systemic lupus erythematosus.J Immunol2006; 177: 7416 – 7422 .
2.
2 Ehrenstein MRJury ECMauri C . Statins for atherosclerosis – as good as it gets?N Engl J Med2005; 352: 73 – 75 [comment].
3.
3 Datta SK . Major peptide autoepitopes for nucleosome-centered T and B cell interaction in human and murine lupus.Ann NY Acad Sci2003; 987: 79 – 90 .
4.
4 Kang H-KMichaels MABerner BRDatta SK . Very low-dose tolerance with nucleosomal peptides controls lupus and induces potent regulatory T cell subsets.J Immunol2005; 174: 3247 – 3255 .
5.
5 Kang HKLiu MData SK . Low-dose peptide tolerance therapy of lupus generates plasmacytoid dendritic cells that cause expansion of autoantigen-specific regulatory T cells and contraction of inflammatory Th17 cells.J Immunol2007; 178: 7849 – 7858 .
6.
6 Leadbetter EARifkin IRHohlbaum AMBeaudette BCShlomchik MJMarshak-Rothstein A . Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors.Nature2002; 416: 595 – 598 .
7.
7 Barton GMKagan JCMedzhitov R . Intracellular localization of Toll-like receptor 9 prevents recognition of self DNA but facilitates access to viral DNA.Nat Immunol2006; 7: 49 – 56 [see comment].
8.
8 Berland RFernandez LKari E . Toll-like receptor 7-dependent loss of B cell tolerance in pathogenic autoantibody knockin mice.Immunity2006; 25: 429 – 440 .
9.
9 Subramanian STus KLi QZ . A Tlr7 translocation accelerates systemic autoimmunity in murine lupus.In: Proceedings of the National Academy of Sciences of the United States of America, vol.103. 2006. p. 9970 – 9975 .
10.
10 Deane JABolland S . Nucleic acid-sensing TLRs as modifiers of autoimmunity.J Immunol2006; 177: 6573 – 6578 .
12 Christensen SRShupe JNickerson KKashgarian MFlavell RAShlomchik MJ . Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus.Immunity2006; 25: 417 – 428 .
13.
13 Sen R . Control of B lymphocyte apoptosis by the transcription factor NF-kappaB.Immunity2006; 25: 871 – 883 .
14.
14 Kim SJGershov DMa XBrot NElkon KB . I-PLA(2) activation during apoptosis promotes the exposure of membrane lysophosphatidylcholine leading to binding by natural immunoglobulin M antibodies and complement activation.J Exp Med2002; 196: 655 – 665 .
15.
15 Jiang NReich CFMonestier MPisetsky DS . The expression of plasma nucleosomes in mice undergoing in vivo apoptosis.Clin Immunol2003; 106: 139 – 147 .
16.
16 Licht Rvan Bruggen MCOppers-Walgreen BRijke TPBerden JH . Plasma levels of nucleosomes and nucleosome-autoantibody complexes in murine lupus: effects of disease progression and lipopolyssacharide administration.Arthritis Rheum2001; 44: 1320 – 1330 .
17.
17 Vinuesa CGCook MCAngelucci C . A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity.Nature2005; 435: 452 – 458 .
19 Iwai HAbe MHirose S . Involvement of inducible costimulator-B7 homologous protein costimulatory pathway in murine lupus nephritis.J Immunol2003; 171: 2848 – 2854 .
20.
20 Zeller GCHirahashi JSchwarting ASharpe AHKelley VR . Inducible co-stimulator null MRL-Faslpr mice: uncoupling of autoantibodies and T cell responses in lupus.J Am Soc Nephrol2006; 17: 122 – 130 .
21.
21 Tada YKoarada STomiyoshi Y . Role of inducible costimulator in the development of lupus in MRL/lpr mice.Clin Immunol2006; 120: 179 – 188 .
22.
22 Gotsman IGrabie NGupta R . Impaired regulatory T-cell response and enhanced atherosclerosis in the absence of inducible costimulatory molecule.Circulation2006; 114: 2047 – 2055 .
23.
23 Kumar KRLi LYan M . Regulation of B cell tolerance by the lupus susceptibility gene Ly108.Science2006; 312: 1665 – 1669 [see comment].
